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The epidermis is the outermost of the three layers that comprise the skin, the inner layers being the dermis and hypodermis. [1] The epidermis layer provides a barrier to infection from environmental pathogens [2] and regulates the amount of water released from the body into the atmosphere through transepidermal water loss.
The stratum spinosum (or spinous layer/prickle cell layer) [1] is a layer of the epidermis found between the stratum granulosum and stratum basale. [2] This layer is composed of polyhedral keratinocytes. [3] [4] These are joined with desmosomes. [3]
In reptiles, the stratum corneum is permanent, and is replaced only during times of rapid growth, in a process called ecdysis or moulting. This is conferred by the presence of beta-keratin, which provides a much more rigid skin layer. In the human forearm, about 1300 cells per cm 2 per hour are shed. [10]
The stratum granulosum (or granular layer) is a thin layer of cells in the epidermis lying above the stratum spinosum and below the stratum corneum (stratum lucidum on the soles and palms). [1] Keratinocytes migrating from the underlying stratum spinosum become known as granular cells in this layer.
The human skin is the outer covering of the body and is the largest organ of the integumentary system. The skin has up to seven layers of ectodermal tissue guarding muscles, bones, ligaments and internal organs. Human skin is similar to most of the other mammals' skin, and it is very similar to pig skin.
Cells in tissues break down and release hydrolytic enzymes, and the top layer of skin may become loosened, leading to skin slippage. [7]: 153–162 Decomposition of the gastrointestinal tract results in a dark, foul-smelling liquid called "purge fluid" that is forced out of the nose and mouth due to gas pressure in the intestine.
Peanut Butter Blossoms. As the story goes, a woman by the name of Mrs. Freda F. Smith from Ohio developed the original recipe for these for The Grand National Pillsbury Bake-Off competition in 1957.
Epithelium or epithelial tissue is a thin, continuous, protective layer of cells with little extracellular matrix. An example is the epidermis, the outermost layer of the skin. Epithelial (mesothelial) tissues line the outer surfaces of many internal organs, the corresponding inner surfaces of body cavities, and the inner surfaces of blood vessels.