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Verrucotoxin (VTX) is a lethal venom produced by the dorsal fins of Synanceia verrucosa. This species of reef stonefish is connected to the family Synanceiidae. The venom of this species of stonefish is a tetrameric glycoprotein with cardiovascular and cytolytic effects. [1]
Synanceia is a genus of ray-finned fish belonging to the subfamily Synanceiinae, the stonefish, which is classified within the family Scorpaenidae, the scorpionfish and relatives. Stonefish are the most venomous fish known; stings can be fatal to humans.
Synanceia verrucosa are usually brown or grey, and may have areas of yellow, orange, or red. [8] The dorsal fin contains between 12 and 14 spines and 5 and 7 soft rays while the anal fin has 3 spines and 5 or 6 soft rays. [2] The dorsal spines are of equal length with a thicker sheath of skin containing the venom glands at their base.
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Synanceiinae, or the family Synanceiidae, was first named and recognised as a grouping of related taxa by the English naturalist William John Swainson in 1839. [1] The 5th edition of Fishes of the World treats this grouping as a subfamily within the family Scorpaenidae, dividing the subfamily into the three tribes: Minoini, Choridactylini and Synanceiini. [3]