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2. The best kojic acid skin care products to brighten skin - AOL

   www.aol.com/news/best-kojic-acid-skin-care...

   This toner takes skin-brightening to the next level by pairing kojic acid with vitamin C — yet another tyrosinase inhibitor — as well as bearberry extract, a plant-based alternative to ...

3. 4-Butylresorcinol - Wikipedia

   en.wikipedia.org/wiki/4-Butylresorcinol

   Hyperpigmentation is believed to be related to the enzyme tyrosinase which produces melanin. Among several chemicals known to inhibit tyrosinase production, such as hydroquinone, arbutin, and kojic acid, 4-butylresorcinol has been found to be the most powerful inhibitor by a wide margin.

4. Skin whitening - Wikipedia

   en.wikipedia.org/wiki/Skin_whitening

   Several skin whitening agents, including tyrosinase inhibitors, have been found to cause an increase in the expression of tyrosinase, which by itself would increase melanin synthesis. [ 41 ] Microphthalmia-associated transcription factor (MITF) is the master transcription factor that controls the expression of TYR, TRP1, and TRP2, MART1 ...

5. 11 dermatologist-approved melasma treatments of 2023

   www.aol.com/news/11-dermatologist-approved...

   Shop the best melasma treatments and serums for hyperpigmentation. Expert-recommended products include La Roche Posay, Neutrogena, SkinCeuticals and more. 11 dermatologist-approved melasma ...

6. This Chronic Skin Condition Is A Common Cause Of Dark ... - AOL

   www.aol.com/chronic-skin-condition-common-cause...

   Use a retinol cream. Retinol increases cell turnover, which can lighten pigmentation. "For melasma, retinol can be used as a stand-alone topical and is also commonly prescribed as a combination ...

7. Arbutin - Wikipedia

   en.wikipedia.org/wiki/Arbutin

   Tyrosinase is an enzyme needed in melanin synthesis in the melanin producing cell of the skin, the melanocyte. By reducing the activity of tyrosinase, β-arbutin reduces the synthesis of melanin, leading to a lighter skin tone and the diminished appearance of hyperpigmentation. It is not as potent an inhibitor of tyrosinase as α-arbutin. [6]

8. Experts Agree: These Are the 11 Best Hyperpigmentation Serums

   www.aol.com/lifestyle/11-best-hyperpigmentation...

   Anti-Aging Repair Serum. This milky serum, created by dermatologist Loretta Ciraldo is clinically proven to improve hyperpigmentation by 60 percent after eight weeks. It combines a non-sensitizing ...

9. Azelaic acid - Wikipedia

   en.wikipedia.org/wiki/Azelaic_acid

   Azelaic acid is used for treatment of skin pigmentation, including melasma and postinflammatory hyperpigmentation, particularly in those with darker skin types. It has been recommended as an alternative to hydroquinone. [23] As a tyrosinase inhibitor, [5] azelaic acid reduces synthesis of melanin. [24]