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There is evidence from systematic review and meta-analyses that statins, particularly atorvastatin, reduce both decline in kidney function (eGFR) and the severity of protein excretion in urine, [28] [29] [30] with higher doses having greater effect. [29] [30] Data are conflicting for whether statins reduce risk of kidney failure. [28]
Commonly recommended statins Explanation Kidney transplantation recipients taking ciclosporin: Pravastatin or fluvastatin: Drug interactions are possible, but studies have not shown that these statins increase exposure to ciclosporin. [60] HIV-positive people taking protease inhibitors: Atorvastatin, pravastatin or fluvastatin
Lipid-lowering agents, also sometimes referred to as hypolipidemic agents, cholesterol-lowering drugs, or antihyperlipidemic agents are a diverse group of pharmaceuticals that are used to lower the level of lipids and lipoproteins, such as cholesterol, in the blood (hyperlipidemia). The American Heart Association recommends the descriptor ...
Statins are a type of medication that help lower low-density lipoprotein (LDL) cholesterol — or “bad” cholesterol — in the body. This helps keep the arteries clear so blood has an easier ...
A new way of determining heart disease risk may result in millions fewer people getting prescriptions for statins, according to new research. Heart doctors warned, however, that more information ...
Cholesterol is a waxy, fat-like substance in the blood produced by the liver and from the food we eat. There are two kinds: low-density lipoprotein or LDL, the “bad” cholesterol, and high ...
For example, antibiotics that kill gut bacteria often reduce enterohepatic drug circulation and this requires a temporary increase of the drug's dose until the antibiotic use is discontinued and the gut repopulates with bacteria. This effect of antibiotics on enterohepatic circulation of other drugs is one of several types of drug interactions.
Statins lower bad cholesterol and thereby decrease the number of fatty deposits in your arteries to prevent plaque buildup that leads to blockages and heart attacks. Antiarrhythmic medications.