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Naltrexone/bupropion, sold under the brand name Contrave among others, is a fixed-dose combination medication for the management of chronic obesity in adults in combination with a reduced-calorie diet and increased physical activity. [4] [6] It contains naltrexone, an opioid antagonist, and bupropion, an aminoketone atypical antidepressant. [4]
Buspirone, sold under the brand name Buspar, among others, is an anxiolytic, a medication primarily used to treat anxiety disorders, particularly generalized anxiety disorder (GAD). [ 10 ] [ 11 ] It is a serotonin 5-HT 1A receptor partial agonist , increasing action at serotonin receptors in the brain. [ 3 ]
Bupropion, when used for treating long-term weight gain over six to twelve months, results in an average weight loss of 2.7 kilograms (6.0 lb) over placebo. [74] This is not much different from the weight loss produced by several other weight-loss medications such as sibutramine or orlistat . [ 74 ]
Keppra (levetiracetam) – an anticonvulsant drug which is sometimes used as a mood stabilizer and has potential benefits for other psychiatric and neurologic conditions such as Tourette syndrome, anxiety disorder, and Alzheimer's disease; Klonopin – anti-anxiety and anti-epileptic medication of the benzodiazepine class
Experts agree that eating wholesome, healthy meals, reducing calories, and increasing physical activity are the best ways to lose weight and keep it off long-term. Still, many people turn to ...
For the first time in over a decade, obesity rates in the United States may finally be heading in the right direction and new weight loss drugs like semaglutide could be part of the reason why. A ...
[84] [85] Preoperative weight loss can reduce operative time and hospital stay. [84] [86] [87] although there is insufficient evidence whether preoperative weight loss may be beneficial to reduce long-term morbidity or complications. [87] [88] Weight loss and decreases in liver size may be independent from the amount of calorie restriction. [85]
The dose of bupropion in the study was lower than the target dose recommended for clinical practice. [10] In this study, dextromethorphan/bupropion showed significantly greater improvement than bupropion alone in the first two weeks of treatment but not by week 6 of treatment in people with major depressive disorder.