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The structure-activity relationship of the drug class has been explored to a reasonable extent. The optimal substitution pattern is fairly tightly defined (i.e. N,N-diethyl on the amine nitrogen, 4-ethoxy on the benzyl ring and 5-nitro on the benzimidazole ring), but even derivatives incorporating only some of these features are still potent opioids.
Pages in category "Benzimidazole opioids" The following 23 pages are in this category, out of 23 total. This list may not reflect recent changes. ...
Benzimidazole opioids (23 P) Pages in category "Benzimidazoles" The following 110 pages are in this category, out of 110 total. This list may not reflect recent ...
Etonitazene, also known as EA-4941 or CS-4640, [2] is a benzimidazole opioid, first reported in 1957, [3] that has been shown to have approximately 1,000 to 1,500 times the potency of morphine in animals. [4] [better source needed]
Etodesnitazene (also known as desnitroetonitazene, etazen, etazene, and etazone) is a benzimidazole-derived opioid analgesic drug, which was originally developed in the late 1950s alongside etonitazene and a range of related derivatives. [1]
Etomethazene (5-methyldesnitroetonitazene, 5-methyl etodesnitazene, Eto) is a benzimidazole derivative with opioid effects which has been sold as a designer drug over the internet since 2022, first being definitively identified in Sweden in January 2023.
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This list may not reflect recent changes. ... List of benzimidazole opioids; List of β-lactam antibiotics; List of drugs: Bi–Bo; List of drugs: Br;