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Anticonvulsants as a group however are known to cause tolerance to the anti-seizure effect. [40] SSRI drugs, which have an important use as antidepressants, engender a discontinuation syndrome that manifests with physical side effects; e.g., there have been case reports of a discontinuation syndrome with venlafaxine (Effexor). [24]
Co-occurring psychiatric disorders are more common among women than men who abuse substances; women more frequently use substances to reduce the negative effects of these co-occurring disorders. Substance abuse puts both men and women at higher risk for perpetration and victimization of sexual violence. [ 108 ]
The latter reflects physical dependence in which the body adapts to the drug, requiring more of it to achieve a certain effect (tolerance) [25] and eliciting drug-specific physical or mental symptoms if drug use is abruptly ceased (withdrawal). Physical dependence can happen with the chronic use of many drugs—including even appropriate ...
The heroin and opioid abuse epidemic is hitting America hard with heroin use more than doubling in the past decade among young adults, according to the CDC.While the dire statistics tell the ...
A Drugs Forum user said the itching side effect subsides with more regular heroin use, but nobody wants to get to that point. "Itching is a really common side effect, but as soon as you start to ...
Substance dependence, also known as drug dependence, is a biopsychological situation whereby an individual's functionality is dependent on the necessitated re-consumption of a psychoactive substance because of an adaptive state that has developed within the individual from psychoactive substance consumption that results in the experience of withdrawal and that necessitates the re-consumption ...
It's important to understand why teens use or misuse drugs, so the right resources and education can help them, Dr. Nora Volkow, director of the National Institute on Drug Abuse, wrote in an email.
Repeated heroin use changes the physical structure and physiology of the brain, creating long-term imbalances in neuronal and hormonal systems that are not easily reversed. Studies have shown some deterioration of the brain's white matter due to heroin use, [ 63 ] which may affect decision-making abilities, the ability to regulate behavior, and ...