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The era of cancer chemotherapy began in the 1940s with the first use of nitrogen mustards and folic acid antagonist drugs. The targeted therapy revolution has arrived, but many of the principles and limitations of chemotherapy discovered by the early researchers still apply.
Learn how chemotherapy evolved from Paul Ehrlich's experiments with arsenicals to the development of combination chemotherapy and adjuvant therapy. The article covers the key events, models, and drugs that shaped the field of cancer chemotherapy from 1900 to 2008.
Chemotherapy was derived from mustard gas, a chemical weapon used in World War II. Learn how chemotherapy evolved from a toxic agent to a cancer treatment and how it is used today.
Learn how chemotherapy was first used to treat cancer in the 1940s, based on the discovery of mustard agents and folate analogues. Find out how chemotherapy evolved over the decades and what...
Learn how Yale researchers discovered the first chemotherapy agent, nitrogen mustard, from mustard gas in World War II. Find out how this breakthrough led to multidrug chemotherapy for Hodgkin's disease and other cancers.
In 1940, Dr. Rhoads served as Director of Memorial Hospital for Cancer Research and in 1945 as the first Director of the new Memorial Sloan Kettering Cancer Center. This is where, “Dr. Rhoads gained national fame as the leader of the war on cancer….
A book by Jennet Conant traces the origins of chemotherapy from a Second World War disaster involving chemical weapons in Bari, Italy. It follows the stories of two physicians who fought to...
The use of chemotherapy to treat cancer began at the start of the 20th century with attempts to narrow the universe of chemicals that might affect the disease by developing methods to screen chemicals using transplantable tumors in rodents.
Emil J. Freireich (March 16, 1927 – February 1, 2021) [1] was an American hematologist, oncologist, and cancer biologist. He was recognized as a pioneer in the treatment of cancer and use of chemotherapy and is often known as the father of modern leukemia therapy.
Chemotherapy made modest progress in the 1960’s, but in 1971 President Richard Nixon, as a distraction from the Vietnam war, promoted his National Cancer Act. It funded a major research drive to “win the war on cancer”.