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Mediastinal lymph nodes: These are lymph nodes situated in the area between the chest wall and the lungs (called the mediastinum). These also include lower mediastinal lymph nodes such as subcarinal lymph nodes surrounding the windpipe (trachea) and peribronchial lymph nodes surrounding the bronchi.
The cancer has also spread to lymph nodes within the lung and/or around the area where the bronchus enters the lung (peribronchial, hilar, and intrapulmonary lymph nodes). These lymph nodes are on the same side as the cancer (N1).
Subcarinal Lymph Nodes Should be Dissected in All Lobectomies for Non-Small Cell Lung Cancer—Regardless of Primary Tumor Location
How Does Lung Cancer Spread to Lymph Nodes? If a cancer cell breaks away from the primary tumor in your lung, your blood or lymph fluid can carry it to a different part of your body. Lymph nodes are often the most common place to which any cancer, including lung cancer, will spread.
Current classification of the “N” component sub-divides it into four divisions, no lymph node metastasis (N0), local peribronchial and/or ipsilateral hilar lymph node metastasis (N1), ipsilateral mediastinal and/or subcarinal lymph node metastasis (N2), and contralateral mediastinal and/or supraclavicular lymph node metastasis (N3).
Thoracic lymph nodes are divided into 14 stations as defined by the International Association for the Study of Lung Cancer (IASLC) 1, principally in the context of oncologic staging. For the purpose of prognostication, the stations may be grouped into seven zones.
Lymph node dissection is used to treat early-stage lung cancer. The present study aimed to investigate if resecting the subcarinal lymph nodes affects prognosis of patients with stage IB non-small cell lung cancer (NSCLC).