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Chromosome 16. Trisomy 16 is a chromosomal abnormality in which there are 3 copies of chromosome 16 rather than two. [1] It is the most common autosomal trisomy leading to miscarriage, and the second most common chromosomal cause (closely following X-chromosome monosomy). [2] About 6% of miscarriages have trisomy 16. [3]
The baby may be born at a low birthweight. [2] Preterm delivery (prior to 37 weeks gestation). [2] The baby may be deprived of oxygen and thus develop asphyxia. [2] Placental abruption may also result in death of the baby, or stillbirth. [2]
Histopathology of placenta with increased syncytial knotting of chorionic villi, with two knots pointed out. The following characteristics of placentas have been said to be associated with placental insufficiency, however all of them occur in normal healthy placentas and full term healthy births, so none of them can be used to accurately diagnose placental insufficiency: [citation needed]
Which leads to serious injuries to both the mother and the new-born. [11] Women who endured placental disease within the first pregnancy has an increased risk of the disease progressing within future pregnancies. [13] The onset of the disease within the first trimester leads to preterm delivery of a premature baby. [14]
Intrauterine hypoxia can be attributed to maternal, placental, or fetal conditions. [12] Kingdom and Kaufmann classifies three categories for the origin of fetal hypoxia: 1) pre-placental (both mother and fetus are hypoxic), 2) utero-placental (mother is normal but placenta and fetus is hypoxic), 3) post-placental (only fetus is hypoxic).
Depending on severity, common symptoms in pregnancy can develop into complications. [1] Pregnancy symptoms may be categorized based on trimester as well as region of the body affected. Each pregnancy can be quite different and many people do not experience the same or all of the symptoms. If a person is concerned about their symptoms they ...
It begins between the 4 and 8 weeks of pregnancy and usually subsides by 14 to 16 weeks. The exact cause of nausea is not fully understood but it correlates with the rise in the levels of human chorionic gonadotropin , progesterone , and the resulting relaxation of smooth muscle of the stomach.
The ANOS1 gene defect (previously known as KAL-1) was the first one discovered and the one most commonly tested for. It causes the x-linked form of Kallmann syndrome and is associated with the additional symptoms of anosmia, bimanual synkinesis and renal agenesis. This defect is thought to be responsible for between 5 and 10% of all Kallmann ...
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