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Dapoxetine, sold under the brand name Priligy among others, is a selective serotonin reuptake inhibitor (SSRI) used for the treatment of premature ejaculation (PE) in men ages 18 to 64 years old. [ 3 ] [ 4 ] [ 5 ] Dapoxetine works by inhibiting the serotonin transporter , increasing serotonin's action at the postsynaptic cleft, and as a ...
Premature ejaculation (PE) is a male sexual dysfunction that occurs when a male expels semen (and most likely experiences orgasm) soon after beginning sexual activity, and with minimal penile stimulation. [1] It has also been called early ejaculation, rapid ejaculation, rapid climax, premature climax and (historically) ejaculatio praecox.
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An array of more subtle and lingering symptoms after orgasm, which do not constitute POIS, may contribute to habituation between mates. They may show up as restlessness, irritability, increased sexual frustration, apathy, sluggishness, neediness, dissatisfaction with a mate, or weepiness [15] over the days or weeks after intense sexual stimulation.
Coitus interruptus, also known as withdrawal, pulling out or the pull-out method, is an act of birth control during penetrative sexual intercourse, whereby the penis is withdrawn from a vagina prior to ejaculation so that the ejaculate may be directed away in an effort to avoid insemination.
An enlarged prostate is common in older men and typically carries symptoms of lower urinary tract problems, which can become bladder problems over time. Tadalafil is typically taken daily for BPH.
Numerous chemical substances influence the IELT. Substances such as alcohol and opioids (e.g. heroin, morphine, oxycodone) depress the central nervous system, prolonging the IELT, while selective serotonin reuptake inhibitors (SSRIs) (e.g. dapoxetine) delay ejaculation by blocking a physiological process connected to ejaculatory inevitability, "the male point of no return".
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