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Nitrofurantoin is an antibacterial medication of the nitrofuran class used to treat urinary tract infections, although it is not as effective for kidney infections. [10] It is taken by mouth. [10] Common side effects include nausea, loss of appetite, diarrhea, and headaches. [10] Rarely numbness, lung problems, or liver problems may occur. [10]
A urinary tract infection (UTI) is an infection that affects a part of the urinary tract. [1] Lower urinary tract infections may involve the bladder (cystitis) or urethra (urethritis) while upper urinary tract infections affect the kidney (pyelonephritis). [10] Symptoms from a lower urinary tract infection include suprapubic pain, painful ...
Urinary tract infection in pediatric patients is a significant clinical issue, affecting approximately 7% of fevered infants and children. [43] If left untreated, the infection can ascend from the bladder to the kidneys, resulting in acute pyelonephritis, which leads to hypertension, kidney scarring, and end-stage kidney disease. [44]
Pyelonephritis is inflammation of the kidney, typically due to a bacterial infection. [ 3 ] Symptoms most often include fever and flank tenderness. [ 2 ] Other symptoms may include nausea, burning with urination, and frequent urination. [ 2 ] Complications may include pus around the kidney, sepsis, or kidney failure.
It is used to treat urinary tract infections, methicillin-resistant Staphylococcus aureus (MRSA) skin infections, travelers' diarrhea, respiratory tract infections, and cholera, among others. [2] [7] It is used both to treat and prevent pneumocystis pneumonia and toxoplasmosis in people with HIV/AIDS and other causes of immunosuppression. [2]
This is because unlike Gram-negative Enterobacteriaceae urinary tract infections, S. saprophyticus does not reduce nitrate and has a longer generation time, thus does not consume glucose as rapidly. Even when such an infection occurs above the neck of the bladder, low numbers of colony-forming units (less than 10 5 cfu/ml) are often present. [8]
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