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Vitamin B 12 deficiency can be found within normal levels, so clinical symptoms should be taken into account when a diagnosis is made. [2] Normal blood levels are considered to be at least above 300 pg/mL in adults. [2] Some researchers have suggested that current standards for vitamin B 12 levels are too low. [152]
[6] [15] [26] Vitamin B 12 deficiency can also cause symptoms of mania and psychosis. [27] [28] Among other problems, weakened immunity, reduced fertility and interruption of blood circulation in women may occur. [29] The main type of vitamin B12 deficiency anemia is pernicious anemia, [30] characterized by a triad of symptoms:
The Good Housekeeping Institute tested more than 30 brands of B12 supplements, and chose Nature made B12 1000mcg as the best overall option, and Garden of Life Vitamin Code Raw B12 as the best ...
Neuropsychiatric symptoms can precede hematological signs and are often the presenting manifestation of the disease. [55] Vitamin B 12 serum levels are used to detect its deficiency, but do not distinguish its causes. Vitamin B 12 levels can be falsely high or low and data for sensitivity and specificity vary widely.
If there are other, reversible causes of low vitamin B 12 levels, the cause must be treated. [106] Vitamin B 12 deficiency anemia is usually easily treated by providing the necessary level of vitamin B 12 supplementation. [107] The injections are quick-acting, and symptoms usually go away within one to two weeks. [107]
Low levels of vitamin D have also been linked to depression, with studies finding that supplementing vitamin D helped reduce depressive symptoms in adults with depression. However, supplementation ...
In general, the most common cause of this condition is a deficiency of vitamin B 12. This may be due to a dietary deficiency, malabsorption in the terminal ileum, lack of intrinsic factor secreted from gastric parietal cells, or low gastric pH inhibiting attachment of intrinsic factor to ileal receptors. [10]
Niacin deficiency is a consequence of a diet low in both niacin and the amino acid tryptophan, a precursor for the vitamin. Low plasma tryptophan is a non-specific indicator, meaning it can have other causes. The signs and symptoms of niacin deficiency start to revert within days of oral supplementation with large amounts of the vitamin. [23] [24]
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