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2. Oxitriptan - Wikipedia

   en.wikipedia.org/wiki/Oxitriptan

   5-HTP's short half-life is impractical for chronic drug therapy. Research conducted at Duke University in mice has demonstrated that 5-HTP when administered as slow-release appears to gain drug properties. [55] Slow-release delivery attenuates or abolishes the peaks and valleys in 5-HTP exposure during treatment. [56]

3. Management of depression - Wikipedia

   en.wikipedia.org/wiki/Management_of_depression

   Small studies have been performed using 5-HTP and tryptophan as adjunctive therapy in addition to standard treatment for depression. While some studies had positive results, they were criticized for having methodological flaws, and a more recent study did not find sustained benefit from their use. [136]

4. List of antidepressants - Wikipedia

   en.wikipedia.org/wiki/List_of_antidepressants

   Oxitriptan [5-Hydroxytryptophan (5-HTP)] (Cincofarm, Levothym, Triptum) – precursor in serotonin biosynthesis Tryptophan (Tryptan, Optimax, Aminomine) – precursor in serotonin biosynthesis Adjunctive treatments

5. 6 different subtypes discovered for depression: How that may ...

   www.aol.com/lifestyle/6-different-subtypes...

   They note that about 30% of people with depression do not adequately respond to treatment. They say the subtypes may help identify potential treatment responses for things such as antidepressants ...

6. 5-Hydroxytryptophan - Wikipedia

   en.wikipedia.org/wiki/5-Hydroxytryptophan

   5-HTP is produced from the amino acid tryptophan through the action of the enzyme tryptophan hydroxylase. Tryptophan hydroxylase is one of the biopterin-dependent aromatic amino acid hydroxylases. Production of 5-HTP is the rate-limiting step in 5-HT (serotonin) synthesis. 5-HTP is normally rapidly converted to 5-HT by amino acid decarboxylase. [1]

7. 5-HT1A receptor - Wikipedia

   en.wikipedia.org/wiki/5-HT1A_receptor

   15550 Ensembl ENSG00000178394 ENSMUSG00000021721 UniProt P08908 Q64264 RefSeq (mRNA) NM_000524 NM_008308 RefSeq (protein) NP_000515 NP_032334 Location (UCSC) Chr 5: 63.96 – 63.96 Mb Chr 13: 105.58 – 105.58 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse The serotonin 1A receptor (or 5-HT 1A receptor) is a subtype of serotonin receptors, or 5-HT receptors, that binds serotonin ...

8. α-Methyl-5-hydroxytryptophan - Wikipedia

   en.wikipedia.org/wiki/Α-methyl-5-hydroxytryptophan

   [1] [2] It is the α-methylated derivative of 5-hydroxytryptophan (5-HTP), while αMS is the α-methylated analogue of serotonin. [1] [2] Along with α-methyltryptophan (α-MTP), α-Me-5-HTP has been suggested for potential therapeutic use in the treatment of conditions thought by some authors to be related to serotonin deficiency, such as ...

9. Carbidopa/oxitriptan - Wikipedia

   en.wikipedia.org/wiki/Carbidopa/oxitriptan

   Carbidopa/oxitriptan (developmental code name EVX-101), or carbidopa/5-hydroxytryptophan (carbidopa/5-HTP), is a combination of 5-hydroxytryptophan (oxitriptan), a serotonin precursor, and carbidopa, a peripherally selective aromatic L-amino acid decarboxylase inhibitor, which is under development as an antidepressant for the treatment of depressive disorders. [1]