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Lorenzo's grandfather, Cosimo de' Medici, was the first member of the Medici family to lead the Republic of Florence and run the Medici Bank simultaneously. As one of the wealthiest men in Europe, the elder Cosimo spent a very large portion of his fortune on government and philanthropy, for example as a patron of the arts and financier of public works. [7]
Lorenzo was born in Florence on 12 September 1492, a son of Piero di Lorenzo de' Medici and Alfonsina Orsini. [2] His paternal grandparents were Lorenzo the Magnificent and Clarice Orsini. [2] His maternal grandparents were Roberto Orsini, Count of Tagliacozzo and his wife, Catherine of San Severino.
Catherine was born in Florence to Lorenzo de' Medici, Duke of Urbino, and Madeleine de La Tour d'Auvergne. In 1533, at the age of 14, Catherine married Henry, the second son of King Francis I and Queen Claude of France, who would become Dauphin of France upon the death of his elder brother Francis in 1536.
Piero di Lorenzo de' Medici was the eldest son of Lorenzo de' Medici (Lorenzo the Magnificent) and Clarice Orsini.He was raised alongside his younger brother Giovanni, who would go on to become Pope Leo X, and his cousin Giulio, who would later become Pope Clement VII.
The Children of Henry VIII by John Guy (Oxford UP, 2013 ISBN 978-0192840905) Children of England: The Heirs of King Henry VIII 1547–1558 by Alison Weir (Jonathan Cape, 1996; Vintage, 2008 ISBN 978-0099532675) Hart, Kelly (2009). The Mistresses of Henry VIII (First ed.). The History Press. ISBN 978-0752448350. Starkey, David (2003).
Henry III, King of France: 19 September 1551: 2 August 1589: Married Louise of Lorraine on 15 February 1575. Had no issue. Briefly King of Poland in 1574. Margaret of France: 14 May 1553: 27 March 1615: Known as "Queen Margot". Married Henry IV, King of France on 18 August 1572 and divorced on 17 December 1599. No issue.
The House of Medici (English: / ˈ m ɛ d ɪ tʃ i / MED-itch-ee, UK also / m ə ˈ d iː tʃ i / mə-DEE-chee; [4] Italian: [ˈmɛːditʃi]) was an Italian banking family and political dynasty that first consolidated power in the Republic of Florence under Cosimo de' Medici and his grandson Lorenzo "the Magnificent" during the first half of the 15th century.
Clarice and Lorenzo had ten children: Lucrezia de' Medici (Florence, 4 August 1470 – 15 November 1553); married Jacopo Salviati on 10 September 1486 and had 10 children, including Cardinal Giovanni Salviati, Cardinal Bernardo Salviati, Maria Salviati (mother of Cosimo I de' Medici, Grand Duke of Tuscany), and Francesca Salviati (mother of Pope Leo XI).