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  2. Melancholia - Wikipedia

    en.wikipedia.org/wiki/Melancholia

    Physiognomy of the melancholic temperament (drawing by Thomas Holloway, c.1789, made for Johann Kaspar Lavater's Essays on Physiognomy). Melancholia or melancholy (from Greek: µέλαινα χολή melaina chole, [1] meaning black bile) [2] is a concept found throughout ancient, medieval, and premodern medicine in Europe that describes a condition characterized by markedly depressed mood ...

  3. Dubin–Johnson syndrome - Wikipedia

    en.wikipedia.org/wiki/Dubin–Johnson_syndrome

    Classically, the condition causes a black liver due to the deposition of a pigment similar to melanin. [2] This condition is associated with a defect in the ability of hepatocytes to secrete conjugated bilirubin into the bile, and is similar to Rotor syndrome. It is usually asymptomatic, but may be diagnosed in early infancy based on laboratory ...

  4. Dyscrasia - Wikipedia

    en.wikipedia.org/wiki/Dyscrasia

    In medicine, both ancient and modern, a dyscrasia is any of various disorders. The word has ancient Greek roots meaning "bad mixture". [1] The concept of dyscrasia was developed by the Greek physician Galen (129–216 AD), who elaborated a model of health and disease as a structure of elements, qualities, humors, organs, and temperaments (based on earlier humorism).

  5. Biliary dyskinesia - Wikipedia

    en.wikipedia.org/wiki/Biliary_dyskinesia

    Biliary dyskinesia is a disorder of some component of biliary part of the digestive system in which bile cannot physically move in the proper direction through the tubular biliary tract. It most commonly involves abnormal biliary tract peristalsis muscular coordination within the gallbladder in response to dietary stimulation of that organ to ...

  6. Bile acid malabsorption - Wikipedia

    en.wikipedia.org/wiki/Bile_acid_malabsorption

    Bile acid malabsorption (BAM), known also as bile acid diarrhea, is a cause of several gut-related problems, the main one being chronic diarrhea. It has also been called bile acid-induced diarrhea, cholerheic or choleretic enteropathy, bile salt diarrhea or bile salt malabsorption.

  7. Gallbladder disease - Wikipedia

    en.wikipedia.org/wiki/Gallbladder_disease

    Gallbladder diseases are diseases involving the gallbladder and is closely linked to biliary disease, with the most common cause being gallstones (cholelithiasis). [1] [2]The gallbladder is designed to aid in the digestion of fats by concentrating and storing the bile made in the liver and transferring it through the biliary tract to the digestive system through bile ducts that connect the ...

  8. Biliary atresia - Wikipedia

    en.wikipedia.org/wiki/Biliary_atresia

    The aflatoxin damaged liver cells and bile duct cells are removed by neutrophil elastase [23] and by involvement of immune system mediators such as CCL-2 or MCP-1, tumor necrosis factor (TNF), interleukin-6 (IL-6), TGF-beta, endothelin (ET), and nitric oxide (NO). Among these, TGF-beta is the most important pro-fibrogenic cytokine that can be ...

  9. Alagille syndrome - Wikipedia

    en.wikipedia.org/wiki/Alagille_syndrome

    Alagille syndrome causes bile duct paucity, which is characterized by narrow and malformed bile ducts. Bile duct paucity causes bile to build up in the liver, resulting in scarring of the liver which hinders the liver's normal functions, like blood filtration and drug metabolism.

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