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The main cause of TB is Mycobacterium tuberculosis (MTB), a small, aerobic, nonmotile bacillus. [8] The high lipid content of this pathogen accounts for many of its unique clinical characteristics. [54] It divides every 16 to 20 hours, which is an extremely slow rate compared with other bacteria, which usually divide in less than an hour. [55]
Mycobacterium tuberculosis (M. tb), also known as Koch's bacillus, is a species of pathogenic bacteria in the family Mycobacteriaceae and the causative agent of tuberculosis. [ 1 ] [ 2 ] First discovered in 1882 by Robert Koch , M. tuberculosis has an unusual, waxy coating on its cell surface primarily due to the presence of mycolic acid .
The medical history includes obtaining the symptoms of pulmonary TB: productive, prolonged cough of three or more weeks, chest pain, and hemoptysis.Systemic symptoms include low grade remittent fever, chills, night sweats, appetite loss, weight loss, easy fatiguability, and production of sputum that starts out mucoid but changes to purulent. [1]
The Huangdi Neijing classic Chinese medical text (c. 400 BCE – 260 CE), traditionally attributed to the mythical Yellow Emperor, describes a disease believed to be tuberculosis, called xulao bing (虛癆病 "weak consumptive disease"), characterized by persistent cough, abnormal appearance, fever, a weak and fast pulse, chest obstructions ...
“The infection might only be in one part of the body and not affect the core temperature enough to cause a fever,” Cohan says. “Other things, like how sensitive each person is to temperature ...
“Having a fever means you have an elevated body temperature,” says Dr. Ricciardi. Dr. Russo points out that there are different variations to a fever, though. “There are low-grade fevers and ...
Tuberculous meningitis, also known as TB meningitis or tubercular meningitis, is a specific type of bacterial meningitis caused by the Mycobacterium tuberculosis infection of the meninges—the system of membranes which envelop the central nervous system.
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