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No new suspicious 18F-FDG avid lesions. If progression by RECIST must verify with follow up; Partial metabolic response (PMR) Reduction of a minimum of 30% in target measurable tumor 18F-FDG SUL peak, with absolute drop in SUL of at least 0.8 SUL units. No increase >30% of SUL or size in all other lesions; No new lesions; Stable metabolic ...
Progressive disease (PD): At least a 20% increase in the sum of the LD of target lesions, taking as reference the smallest sum LD recorded since the treatment started or the appearance of one or more new lesions; Evaluation of non-target lesions. Complete response (CR): Disappearance of all non-target lesions and normalization of tumor marker level
A myeloid sarcoma (chloroma, granulocytic sarcoma, [1]: 744 extramedullary myeloid tumor) is a solid tumor composed of immature white blood cells [2] called myeloblasts. A chloroma is an extramedullary manifestation of acute myeloid leukemia ; in other words, it is a solid collection of leukemic cells occurring outside of the bone marrow .
In the United States in 2012, it was estimated that there was an incidence of 12,000 new cases, and 1,300 deaths, from cancer among children 0 to 14 years of age. [64] Cancer is the second leading cause of death in males and fourth in women under the age of 20 in the United States. The survival rate of children with cancer has improved since ...
Epithelioid sarcoma is a slow-growing and relatively painless tumor, often resulting in a lengthy period of time between presentation and diagnosis. [8] Due to the difficulty of discerning this cancer as different from more common cancers, such as cancers of the skin (squamous cell carcinoma or basal cell carcinoma), it is often misdiagnosed, mistaken as a persistent wart or cyst.
Blastic plasmacytoid dendritic cell neoplasm occurs in children, [5] including neonates, [7] but is more common in adults, particularly those between the ages 60–80. [5] BPDCN usually (i.e. 61% [ 5 ] to 90% [ 8 ] of cases) presents with skin lesions, i.e. nodules, tumors, red or purple papules , bruise-like patches, and/or ulcers that most ...
Pilocytic astrocytoma (and its variant pilomyxoid astrocytoma) is a brain tumor that occurs most commonly in children and young adults (in the first 20 years of life). They usually arise in the cerebellum, near the brainstem, in the hypothalamic region, or the optic chiasm, but they may occur in any area where astrocytes are present, including the cerebral hemispheres and the spinal cord.
Medulloblastoma is the second-most frequent brain tumor in children after pilocytic astrocytoma [37] and the most common malignant brain tumor in children, comprising 14.5% of newly diagnosed brain tumors. [38] In adults, medulloblastoma is rare, comprising fewer than 2% of CNS malignancies. [39]