enow.com Web Search

Search results

  1. Results from the WOW.Com Content Network
  2. Biopharmaceutics Classification System - Wikipedia

    en.wikipedia.org/wiki/Biopharmaceutics...

    The drugs are classified in BCS on the basis of solubility and permeability. Solubility class boundaries are based on the highest dose strength of an immediate release product. A drug is considered highly soluble when the highest dose strength is soluble in 250 ml or less of aqueous media over the pH range of 1 to 6.8.

  3. Absorption (pharmacology) - Wikipedia

    en.wikipedia.org/wiki/Absorption_(pharmacology)

    The stablest crystalline polymorph has the lowest dissolution rate. Dissolution also differs between anhydrous and hydrous forms of a drug. Anhydrous forms often dissolve faster but sometimes are less soluble. Esterification is also used to control solubility. For example, stearate and estolate esters of drugs have decreased solubility in ...

  4. Route of administration - Wikipedia

    en.wikipedia.org/wiki/Route_of_administration

    The chemical properties are solubility, stability, pH, irritancy etc. Site of desired action: the action may be localised and approachable or generalised and not approachable. Rate of extent of absorption of the drug from different routes. Effect of digestive juices and the first pass metabolism of drugs. Condition of the patient.

  5. Bioavailability - Wikipedia

    en.wikipedia.org/wiki/Bioavailability

    Interactions with other drugs/foods: Interactions with other drugs (e.g., antacids, alcohol, nicotine) Interactions with other foods (e.g., grapefruit juice, pomello, cranberry juice, brassica vegetables) Transporters: Substrate of efflux transporters (e.g. P-glycoprotein) Health of the gastrointestinal tract; Enzyme induction/inhibition by ...

  6. Solubility chart - Wikipedia

    en.wikipedia.org/wiki/Solubility_chart

    The following chart shows the solubility of various ionic compounds in water at 1 atm pressure and room temperature (approx. 25 °C, 298.15 K). "Soluble" means the ionic compound doesn't precipitate, while "slightly soluble" and "insoluble" mean that a solid will precipitate; "slightly soluble" compounds like calcium sulfate may require heat to precipitate.

  7. Druglikeness - Wikipedia

    en.wikipedia.org/wiki/Druglikeness

    Solubility in water can be estimated from the number of hydrogen bond donors vs. alkyl sidechains in the molecule. Low water solubility translates to slow absorption and action. Too many hydrogen bond donors, on the other hand, lead to low fat solubility, so that the drug cannot penetrate the cell membrane to reach the inside of the cell.

  8. What to Know About the FDA’s New Definition of ‘Healthy’ Foods

    www.aol.com/know-fda-definition-healthy-foods...

    The U.S. Food and Drug Administration (FDA) announced a new definition of “healthy” food for the first time in 30 years. The new definition will apply to manufacturers who want to call their ...

  9. Dissolution testing - Wikipedia

    en.wikipedia.org/wiki/Dissolution_testing

    In the pharmaceutical industry, drug dissolution testing is routinely used to provide critical in vitro drug release information for both quality control purposes, i.e., to assess batch-to-batch consistency of solid oral dosage forms such as tablets, and drug development, i.e., to predict in vivo drug release profiles. [1]