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Frovatriptan, sold under the brand name Frova, is a triptan drug developed by Vernalis for the treatment of migraine headaches [1] and for short term prevention of menstrual migraine. [2] The product is licensed to Endo Pharmaceuticals in North America and Menarini in Europe.
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Triptans are a family of tryptamine-based drugs used as abortive medication in the treatment of migraines and cluster headaches. They are selective 5-hydroxytryptamine/serotonin 1B/1D (5-HT 1B/1D) agonists. [1] Migraine is a complex disease which affects about 15% of the population and can be highly disabling. [2]
The most common adverse effect is recurrence of migraine. A systematic review found that "rizatriptan 10 mg was the only triptan with a recurrence rate greater than that of placebo". [24] There is a theoretical risk of coronary spasm in patients with established heart disease, and cardiac events after taking triptans may rarely occur. [25]
Migraines are more than an average headache for people like Lisa Simeone. "I get tugging right at the base of my skull," said Simeone. Nearly 40 million Americans battle the condition, according ...
Researchers found the prevalence of migraines in the past three decades has remained stable, but found Migraine Disability Assessment Scale scores, which measure how migraines affect a person ...
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