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Frovatriptan, sold under the brand name Frova, is a triptan drug developed by Vernalis for the treatment of migraine headaches [1] and for short term prevention of menstrual migraine. [2] The product is licensed to Endo Pharmaceuticals in North America and Menarini in Europe.
The most common adverse effect is recurrence of migraine. A systematic review found that "rizatriptan 10 mg was the only triptan with a recurrence rate greater than that of placebo". [24] There is a theoretical risk of coronary spasm in patients with established heart disease, and cardiac events after taking triptans may rarely occur. [25]
The selection of anti-migraine drug for patients depends on their symptoms. The first selective 5-HT 1B/1D agonist, sumatriptan, was first synthesized as a subcutaneous injection, then as an oral tablets and more recently as a nasal spray, it is also available in some countries as suppositories.
Migraines are more than an average headache for people like Lisa Simeone. "I get tugging right at the base of my skull," said Simeone. Nearly 40 million Americans battle the condition, according ...
Rescue treatment involves acute symptomatic control with medication. [4] Recommendations for rescue therapy of migraine include: (1) migraine-specific agents such as triptans, CGRP antagonists, or ditans for patients with severe headaches or for headaches that respond poorly to analgesics, (2) non-oral (typically nasal or injection) route of administration for patients with vomiting, (3) avoid ...
With chronic headache patients, the acupuncturist may needle "tender points at or near the site of maximal headache pain". [25] A study conducted by the University of North Carolina School of Medicine found that compared to medicinal treatment alone, medicinal treatment plus acupuncture resulted in more improvement for chronic daily headache ...
This treatment essentially disrupts the aura phase of migraine before patients develop full-blown migraine attack. [85] In about 74% of the migraine headaches, TMS was found to eliminate or reduce nausea and sensitivity to noise and light. [86] Their research suggests that there is a strong neurological component to migraine.
Eletriptan, sold under the brand name Relpax and used in the form of eletriptan hydrobromide, is a second-generation triptan medication intended for treatment of migraine headaches. [3] [4] It is used as an abortive medication, blocking a migraine attack which is already in progress.
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