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Common side effects include nausea, feeling tired, fever, increased risk of infection, low white blood cell counts, and breakdown of the skin inside the mouth. [4] Other side effects may include liver disease, lung disease, lymphoma, and severe skin rashes. [4] People on long-term treatment should be regularly checked for side effects. [4]
Methotrexate-induced papular eruption appears in patients being treated with methotrexate, such as those with rheumatic disease, presenting with erythematous indurated papules, usually located on the proximal extremities. [1] It has been suggested that it may represent a cutaneous small-vessel vasculitis. [2]
Methotrexate is a folic acid analogue. ... tuberculin skin reaction), and the graft-versus-host disease ... There are also other side-effects, such as hypertension, ...
Less common side-effects include red skin , dry skin ... Jane C. Wright pioneered the use of the drug methotrexate to treat breast cancer and skin cancer.
8 Autoimmune Diseases That Cause Hair Loss. This article was reviewed by Knox Beasley, MD.. You might associate autoimmune conditions with symptoms like skin disease, chronic pain, and fatigue.
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Both high-folate diets and supplemental folic acid may help reduce the toxic side-effects of low-dose methotrexate without decreasing its effectiveness. [ 8 ] [ 9 ] Anyone taking low-dose methotrexate for the health problems listed above should consult with a physician about the need for a folic acid supplement.
As of 2016, treatments for amyopathic dermatomyositis in adults did not have a strong evidence base; published treatments included antimalarial medications, steroids, taken or orally or applied to the skin, calcineurin inhibitors applied to the skin, dapsone, intravenous immunoglobulin, methotrexate, azathioprine, and mycophenolate mofetil ...
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