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Polymyxin B/trimethoprim, sold under the brand name Polytrim is an antimicrobial solution for topical ophthalmic use in the treatment of acute bacterial conjunctivitis and blepharoconjunctivitis. [1] In 2022, it was the 252nd most commonly prescribed medication in the United States, with more than 1 million prescriptions. [2] [3]
Neomycin/polymyxin B/hydrocortisone, sold under the brand Otosporin among others, is a medication used to treat otitis externa (swimmer's ear) and certain eye disorders. [2] [3] It consists of the antibiotics neomycin and polymyxin B, and the steroid hydrocortisone. [3] It is used as an ear drop or eye drop. [2] [3]
Polymyxin B, sold under the brand name Poly-Rx among others, is an antibiotic used to treat meningitis, pneumonia, sepsis, and urinary tract infections. [1] While it is useful for many Gram negative infections, it is not useful for Gram positive infections. [ 1 ]
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Neomycin/polymyxin B/bacitracin, also known as triple antibiotic ointment, is an antibiotic medication used to reduce the risk of infections following minor skin injuries. [ 1 ] [ 2 ] It contains the three antibiotics neomycin , polymyxin B , and bacitracin . [ 1 ]
Bacitracin/polymyxin B (trade name Polysporin among others) is a topical antibiotic cream or ointment. [1] The active ingredients are polymyxin B , bacitracin and occasionally garamycin or gramicidin .
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Polymyxin B1, in turn, comprises several isomers, like isoleucine-polymyxin B1 and B1-1. [15] The major impediment in the purification and isolation of one isomer is due to the minimal structural differences between Polymyxin B1 and B2, differing only in one carbon at the 6th position of the fatty acyl side chain linked to the D-Phenylalanine ...
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