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Bupropion/zonisamide (former tentative brand name Empatic, Excalia) is an experimental combination of bupropion which was under development for the treatment of obesity. [1] [2] [3] Bupropion is a norepinephrine–dopamine reuptake inhibitor and nicotinic acetylcholine receptor antagonist, while zonisamide is an anticonvulsant acting as a sodium channel blocker, T-type calcium channel blocker ...
Zonisamide is an antiseizure drug chemically classified as a sulfonamide and unrelated to other antiseizure agents. The precise mechanism by which zonisamide exerts its antiseizure effect is unknown, although it is believed that the drug blocks sodium and T-type calcium channels , which leads to the suppression of neuronal hypersynchronization ...
Costway Freestanding Wooden 4-Drawer Storage Cabinet. $80 $160 Save $80. ... The 20 best Walmart deal to shop this week; Show comments. Advertisement. In Other News. Entertainment. Entertainment.
The lever comes off for easy cleaning and the cord can be stowed away in the device's built-in storage compartment. "I absolutely love this can opener!" wrote one early shopper.
A refrigerator with a crisper drawer at the bottom of its main compartment Open crisper drawers. A crisper drawer (also known as a crisper) is a compartment within a refrigerator designed to prolong the freshness of stored produce. Crisper drawers have a different level of humidity from the rest of the refrigerator, optimizing freshness in ...
10 Best Canned Tunas, Ranked. This list is based on conversations with the expert dietitians we consulted for this article. The tunas are ranked based on fat and sodium with additional tasting ...
Succinimides refers to compounds that contain the succinimide group. These compounds have some notable uses. Several succinimides are used as anticonvulsant drugs, including ethosuximide, phensuximide, and methsuximide.
Ethoxzolamide, a sulfonamide, inhibits carbonic anhydrase activity in proximal renal tubules to decrease reabsorption of water, sodium, potassium, bicarbonate. It also decreases carbonic anhydrase in the CNS, increasing the seizure threshold.