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The term seizure threshold is used to describe the balance between excitatory (glutaminergic) and inhibitory (GABA-ergic) forces in the brain which affect how susceptible a person is to seizures. Those diagnosed with epilepsy or certain other neurological conditions are more vulnerable to seizures if the threshold is reduced, and should be ...
23334 230676 Ensembl ENSG00000198198 ENSMUSG00000033253 UniProt Q5T011 A2A9C3 RefSeq (mRNA) NM_001012960 NM_001012961 NM_015284 NM_182518 NM_001365999 NM_198170 RefSeq (protein) NP_056099 NP_001352928 NP_937813 Location (UCSC) Chr 1: 43.39 – 43.45 Mb Chr 4: 118.22 – 118.27 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Seizure threshold 2 homolog is a protein that in humans is ...
Cyclobenzaprine, sold under several brand names including, historically, Flexeril, is a muscle relaxer used for muscle spasms from musculoskeletal conditions of sudden onset. [5] It is not useful in cerebral palsy. [5] It is taken by mouth. [5] Common side effects include headache, feeling tired, dizziness, and dry mouth. [5]
The vagus nerve stimulator is a device that can be implanted into patients with epilepsy, especially that which originates from a specific part of the brain. However, both of these treatment options can cause severe adverse effects. Additionally, while seizure frequency typically decreases, they often do not stop entirely. [40] [41]
A seizure may increase the likelihood that more seizures will occur; an old saying in epilepsy research is "seizures beget seizures". [1] Repeated stimulation "lowers the threshold" for more seizures to occur. [4] The brains of experimental animals are repeatedly stimulated, usually with electricity, to induce the seizures. [1]
Antipsychotics are not recommended for benzodiazepine withdrawal (or other CNS depressant withdrawal states) especially clozapine, olanzapine or low potency phenothiazines, e.g., chlorpromazine as they lower the seizure threshold and can worsen withdrawal effects; if used extreme caution is required. [155]
Trump signed an executive order to cut U.S. aid to South Africa, which provided for U.S. resettlement of some "victims of racial discrimination."
Serious side effects may include the potentially permanent movement disorder tardive dyskinesia, neuroleptic malignant syndrome, severe lowering of the seizure threshold, and low white blood cell levels. [6] In older people with psychosis as a result of dementia, it may increase the risk of death. [6] It is unclear if it is safe for use in ...