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The term seizure threshold is used to describe the balance between excitatory (glutaminergic) and inhibitory (GABA-ergic) forces in the brain which affect how susceptible a person is to seizures. Those diagnosed with epilepsy or certain other neurological conditions are more vulnerable to seizures if the threshold is reduced, and should be ...
It has been commonly used to induce deep sedation or general anesthesia for surgery and dental procedures. Unlike many other barbiturates, methohexital actually lowers the seizure threshold, a property that makes it particularly useful when anesthesia is provided for an electroconvulsive therapy (ECT). [4]
Methocarbamol and orphenadrine are each used in more than 250,000 U.S. emergency department visits for lower back pain each year. [22] In the United States, low back pain is the fifth most common reason for all physician visits and the second most common symptomatic reason. [ 23 ]
The vagus nerve stimulator is a device that can be implanted into patients with epilepsy, especially that which originates from a specific part of the brain. However, both of these treatment options can cause severe adverse effects. Additionally, while seizure frequency typically decreases, they often do not stop entirely. [40] [41]
Harmful metabolite called laudanosine (lowering seizure threshold); greater accumulation in individuals with renal failure; Cisatracurium (Nimbex) 90 60–80 does not cause release of histamine refrigerated Vecuronium (Norcuron) 60 30–40 [13] Few, [13] may cause prolonged paralysis [13] and promote muscarinic block widely [13] non-refrigerated
Literature from the 1950s raised concerns about phenothiazine-induced seizures in human patients. For this reason, caution has typically been advised when contemplating acepromazine use in epileptic canine patients, as it was widely believed to lower the seizures threshold.
Brian Monahan, the Capitol’s attending physician, said Senate Minority Leader Mitch McConnell (R-Ky.) does not have a seizure disorder and did not suffer a stroke after a medical episode last week.
Breakthrough seizures are more likely with a number of triggers. [54]: 57 Often when a breakthrough seizure occurs in a person whose seizures have always been well controlled, there is a new underlying cause to the seizure. [55] Breakthrough seizures vary. Studies have shown the rates of breakthrough seizures ranging from 11 to 37%. [56]
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