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Oversaturation of urine with crystals is by far the biggest factor in stone formation in dogs and cats. [3] This oversaturation can be caused by increased excretion of crystals by the kidneys, water reabsorption by the renal tubules resulting in concentration of the urine, and changes in urine pH that influence crystallization.
These signs and symptoms consist of 1) hematuria- blood in the urine, 2) flank pain – pain in the side due to kidney pain, 3) renal colic – intense, cramping pain due to stones in the urinary tract, 4) obstructive uropathy- urinary tract disease due to obstruction, and 5) urinary tract infections.
In dogs, around 1% of diagnosed cancers are bladder cancer. [73] Shetland sheepdogs, beagles, and various terriers are at increased risk relative to other breeds. Signs of a bladder tumor – blood in the urine, frequent urination, or trouble urinating – are common to other canine urinary conditions, and so diagnosis is often delayed. [73]
Diagnostic tests typically include complete blood tests, urinalysis, urine culture, X-rays of the abdomen and chest, and bladder imaging. The definitive diagnosis of bladder cancer will require a tissue biopsy and subsequent examination of the cells under the microscope. [2]
Hematuria can be classified according to visibility, anatomical origin, and timing of blood during urination. [1] [6]In terms of visibility, hematuria can be visible to the naked eye (termed "gross hematuria") and may appear red or brown (sometimes referred to as tea-colored), or it can be microscopic (i.e. not visible but detected with a microscope or laboratory test).
Cancer of the bladder, prostate or ureters can gradually obstruct urine output. Cancers often present with blood in the urine, weight loss, lower back pain or gradual distension in the flanks. [24] Urinary retention in females is uncommon, occurring 1 in 100,000 every year, with a female-to-male incidence rate of 1:13. It is usually transient.
In male dogs, the tumor affects the penis and foreskin. In female dogs, it affects the vulva. Rarely, the mouth or nose are affected. [10] The tumor often has a cauliflower-like appearance. Signs of genital TVT include a discharge from the prepuce and in some cases urinary retention caused by blockage of the urethra. [11]
In dogs and cats, eggs of Capillaria plica are released in the urine of the mammalian definitive host. First stage larvae (L1) develop within the eggshell in 30–36 days. When eaten by the intermediate host-- earthworms of the genera Lumbricus or Dendrobaena—the L1 larvae hatch in the earthworm's intestine.
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