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Carbimazole (brand names Neo-Mercazole, Anti-Thyrox, etc.) is used to treat hyperthyroidism. Carbimazole is a pro-drug as after absorption it is converted to the active form, methimazole . Methimazole prevents thyroid peroxidase enzyme from iodinating and coupling the tyrosine residues on thyroglobulin , hence reducing the production of the ...
Other side effects include granulocytopenia (dose dependent, which improves on cessation of the drug) and aplastic anemia, and in case of propylthiouracil, severe, fulminant liver failure. [20] Patients on these medications should see a doctor if they develop sore throat or fever. The most common side effects are rash and peripheral neuritis. [21]
Thyroid disease is a medical condition that affects the function of the thyroid gland.The thyroid gland is located at the front of the neck and produces thyroid hormones [1] that travel through the blood to help regulate many other organs, meaning that it is an endocrine organ.
Additional side effects can result from interaction with other drugs, such as the possibility of tendon damage from the administration of a quinolone antibiotic with a systemic corticosteroid. [ 51 ] Some antibiotics may also damage the mitochondrion , a bacteria-derived organelle found in eukaryotic, including human, cells. [ 52 ]
Carbimazole, drug used to treat hyperthyroidism; Mafenide, a sulfonamide-type medication used as an antibiotic This page was last edited on 21 August 2020, at 23:30 ...
COX-2 selective inhibitors have fewer gastrointestinal side effects, but promote thrombosis, and some of these agents substantially increase the risk of heart attack. As a result, certain COX-2 selective inhibitors—such as rofecoxib —are no longer used due to the high risk of undiagnosed vascular disease . [ 11 ]
Those who developed significant side effects may also have problems with propylthiouracil. [2] Thiamazole is a cyclic thiourea derivative that works by decreasing the production of thyroid hormones. [2] Thiamazole was approved for medical use in the United States in 1950. [2] It is on the World Health Organization's List of Essential Medicines.
Side effects may occur from excessive doses. [2] This may include weight loss, fever, headache, anxiety, trouble sleeping, arrhythmias, and heart failure. [2] Use in pregnancy and breastfeeding is generally safe. [3] [2] Liothyronine was approved for medical use in 1956. [2] It is available as a generic medication. [3]