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The mifepristone-misoprostol combination is, by far, the most recommended drug regimen for medical abortions, but other drug combinations are available. Misoprostol alone, without mifepristone, may be used in some circumstances for medical abortion, and has even been demonstrated to be successful in the second trimester. [37]
Mifepristone is one of two drugs used in medication abortion in the U.S. But mifepristone has many uses in reproductive care and in other contexts, experts say.
In 2000, GenBioPro's generic version of mifepristone was approved for medication abortion, as part of a two-drug regimen in combination with misoprostol. In 2023, GenBioPro sued the FDA to obtain a legal judgement confirming that mifepristone could continue to be sold, in spite of anti-abortion laws passed in some states.
[2] Common abortifacients used in performing medical abortions include mifepristone, which is typically used in conjunction with misoprostol in a two-step approach. [3] Synthetic oxytocin, which is routinely used safely during term labor, is also commonly used to induce abortion in the second or third trimester. [4]
The most common adverse effects include abdominal pain, feeling tired, and vaginal bleeding. [8] Serious side effects may include heavy vaginal bleeding, bacterial infection, and, if pregnant, birth defects. [8] When used, appropriate follow-up care needs to be available. [8] [14] Mifepristone is primarily an antiprogestogen. [8]
Misoprostol is recommended due to its cost, effectiveness, stability, and low rate of side effects. [50] Oxytocin must also be given by injection, while misprostol can be given orally or rectally for this use, making it much more useful in areas where nurses and physicians are less available. [51]
Aid Access is a nonprofit organization that provides access to medication abortion by mail to the United States and worldwide. It describes its work as a harm reduction strategy designed to provide safe access to mifepristone and misoprostol for those able to become pregnant in the United States who may not otherwise have access to abortion or miscarriage management services. [2]
Rapid tests: The test kit prompts you to collect a sample at home (a nose or throat swab) and you perform the test using provided materials. You get results in a few minutes, which is why these ...