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Diphenhydramine is among prohibited and controlled substances in the Republic of Zambia, [100] and travelers are advised not to bring the drug into the country. Several Americans have been detained by the Zambian Drug Enforcement Commission for possession of Benadryl and other over-the-counter medications containing diphenhydramine. [101]
Benadryl can also be found in a topical form including gels and creams. Benadryl Itch Stopping Cream is a topical cream used to provide temporary itch relief for allergies, hives or even some insect bites. It can be found in the United States and Canada. This topical medication contains 2% of diphenhydramine hydrochloride and 1% of zinc acetate.
Diphenhydramine is the primary constituent of dimenhydrinate and dictates the primary effect. The main differences relative to pure diphenhydramine are a lower potency due to being combined with 8-chlorotheophylline (by weight, dimenhydrinate is between 53% and 55.5% diphenhydramine) [10] and the fact that the stimulant properties of 8-chlorotheophylline help reduce the side ...
Antihistamines are drugs which treat allergic rhinitis, common cold, influenza, and other allergies. [1] Typically, people take antihistamines as an inexpensive, generic (not patented) drug that can be bought without a prescription and provides relief from nasal congestion, sneezing, or hives caused by pollen, dust mites, or animal allergy with few side effects. [1]
The medication is delivered chemically by the salt doxylamine succinate and is taken by mouth. Doxylamine and other first-generation antihistamines are the most widely used sleep medications in the world. [6] Typical side effects of doxylamine (at recommended doses) include dizziness, drowsiness, grogginess, and dry mouth, among others. [7] [4]
In 2005, diphenhydramine was included on a list of first-generation antihistamines that could be used to self-prescribe for mild anxiety and mild depression, with the caveat that self-medicating is only part of self-management of a medical issue.
Stelazine (trifluoperazine) – an antipsychotic used in the treatment of psychotic disorders, anxiety, and nausea caused by chemotherapy [2] Strattera (atomoxetine) – a non-stimulant medication used to treat ADHD; Suboxone (buprenorphine/naloxone) - a partial opioid agonist used in the treatment of opioid use disorder
H 1 antagonists, also called H 1 blockers, are a class of medications that block the action of histamine at the H 1 receptor, helping to relieve allergic reactions.Agents where the main therapeutic effect is mediated by negative modulation of histamine receptors are termed antihistamines; other agents may have antihistaminergic action but are not true antihistamines.