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Following a single oral dose of sertraline, mean peak blood levels of sertraline occur between 4.5 and 8.4 hours. [5] Bioavailability is likely linear and dose-proportional over a dose range of 150 to 200 mg. [ 5 ] Concomitant intake of sertraline with food slightly increases sertraline peak levels and total exposure. [ 5 ]
BE AWARE that sertraline can potentially have drug interactions with a wide range of other medications, substances or supplements, like alcohol, monoamine oxidase inhibitors (MAOIs), nonsteroidal ...
Sertraline. Sold under the brand ... They’ll tell you how to safely reduce your dosage and stop using your medication without developing withdrawal syndrome. ... there are a wide range of common ...
To cross-taper, you’ll need to gradually reduce the dosage of your old antidepressant while gradually increasing the dosage of your new medication at the same time. This technique may be used if ...
[83] [85] [86] Higher doses of antidepressants seem to be more likely to produce emotional blunting than lower doses. [83] It can be decreased by reducing dosage, discontinuing the medication, or switching to a different antidepressant that may have less propensity for causing this side effect. [83]
Generally, tapering is done is to avoid or minimize withdrawal symptoms that arise from neurobiological adaptation to the drug. [ 1 ] [ 2 ] Prescribed psychotropic drugs that may require tapering due to this physical dependence include opioids , [ 3 ] [ 4 ] [ 5 ] selective serotonin reuptake inhibitors , [ 6 ] antipsychotics , [ 7 ...
Drug titration is the process of adjusting the dose of a medication for the maximum benefit without adverse effects. [ 1 ] When a drug has a narrow therapeutic index , titration is especially important, because the range between the dose at which a drug is effective and the dose at which side effects occur is small. [ 2 ]
Most of the time, you can treat performance issues by adjusting your dosage of Zoloft, taking a “drug holiday” or trying a different type of antidepressant drug.
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