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Fluconazole was patented in 1981 and came into commercial use in 1988. [7] It is on the World Health Organization's List of Essential Medicines. [8] Fluconazole is available as a generic medication. [5] In 2022, it was the 160th most commonly prescribed medication in the United States, with more than 3 million prescriptions. [9] [10]
Tinea cruris (TC), also known as jock itch, is a common type of contagious, superficial fungal infection of the groin and buttocks region, which occurs predominantly but not exclusively in men and in hot-humid climates. [3] [4] Typically, over the upper inner thighs, there is an intensely itchy red raised rash with a scaly well-defined curved ...
In the German sprachraum this condition is called tinea inguinalis (from Latin inguen = groin) whereas tinea cruris is used for a dermatophytosis of the lower leg (Latin crus). [13] Tinea cruris is similar to Candidal intertrigo, which is an infection of the skin by Candida albicans.
Dermatophytosis, also known as tinea and ringworm, is a fungal infection of the skin [2] (a dermatomycosis), that may affect skin, hair, and nails. [1] Typically it results in a red, itchy, scaly, circular rash. [1]
Tinea infections can be combatted orally or topically with numerous different medications. Some topical treatments include Mentax 1%, Lamisil 1%, Naftin 1% and Spectazole and these creams should be applied two times a day until the infection is gone. Oral treatments for Tinea include Lamisil, Sporanox, and Diflucan.
One of the most frequent forms is dermatophytosis (ringworm, tinea) which includes tinea pedis, also known as athlete's foot. Another example is cutaneous candidiasis. These fungal infections impair superficial layers of the skin, hair and nails. [1] Dermatomycosis is one of the most common types of infection worldwide. [2]
Before oral antifungal therapies are used to treat nail disease, a confirmation of the fungal infection should be made. [36] Approximately half of suspected cases of fungal infection in nails have a non-fungal cause. [36] The side effects of oral treatment are significant and people without an infection should not take these drugs. [36]
The fungus was first isolated in 1870 from a tinea cruris patient in Germany by Carl Otto Harz, who named it Acrothecium floccosum. [10] Being unaware of Harz's work, Castellani and Sabouraud identified the species again in 1905 and 1907, respectively, and both placed the fungus into the genus Epidermophyton. [11]