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Poliomyelitis (/ ˌ p oʊ l i oʊ ˌ m aɪ ə ˈ l aɪ t ɪ s / POH-lee-oh-MY-ə-LY-tiss), commonly shortened to polio, is an infectious disease caused by the poliovirus. [1] Approximately 75% of cases are asymptomatic; [5] mild symptoms which can occur include sore throat and fever; in a proportion of cases more severe symptoms develop such as headache, neck stiffness, and paresthesia.
The polio vaccine has all but obliterated the illness that once killed thousands and paralyzed 15,000 people nationwide every year. Polio is a deadly disease with a vaccine that RFK Jr.’s ...
The virus infects the throat and intestines, and can cause flu-like symptoms. Paralysis from the polio virus is rare. This year, polio cases have been detected in New York state, London and Jerusalem.
Polio has been a common childhood vaccine since the 1950s, but do adults need a polio booster? What about if you’re planning to travel? Infectious disease experts break it down.
The protein has several domains of which domain D1 contains the polio virus binding site. Within this domain, 37 amino acids are responsible for binding the virus. Poliovirus is an enterovirus. Infection occurs via the fecal–oral route, meaning that one ingests the virus and viral replication occurs in the gastrointestinal tract. [42]
In addition, a vaccine against a given disease may not be recommended for general use in a given country, or may be recommended only to certain populations, such as young children or older adults. Every country makes its own immunization recommendations, based on the diseases that are common in its area and its healthcare priorities.
Post-polio syndrome (PPS, poliomyelitis sequelae) is a group of latent symptoms of poliomyelitis (polio), occurring in more than 80% of polio infections. The symptoms are caused by the damaging effects of the viral infection on the nervous system and typically occur 15 to 30 years after an initial acute paralytic attack.
“The oral polio vaccine is not used in the U.S. because it is live attenuated vaccine, meaning that it exposes the body to a weakened version of the virus leading to an immune response and not ...