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  2. Narcolepsy - Wikipedia

    en.wikipedia.org/wiki/Narcolepsy

    Narcolepsy is a chronic neurological disorder that impairs the ability to regulate sleep–wake cycles, and specifically impacts REM (rapid eye movement) sleep. [1] The pentad symptoms of narcolepsy include excessive daytime sleepiness (EDS), sleep-related hallucinations, sleep paralysis, disturbed nocturnal sleep (DNS), and cataplexy. [1]

  3. Excessive daytime sleepiness - Wikipedia

    en.wikipedia.org/wiki/Excessive_daytime_sleepiness

    Causes Narcolepsy , idiopathic hypersomnia , circadian rhythm sleep disorder , sleep apnea , others Excessive daytime sleepiness ( EDS ) is characterized by persistent sleepiness and often a general lack of energy, even during the day after apparently adequate or even prolonged nighttime sleep.

  4. Orexin - Wikipedia

    en.wikipedia.org/wiki/Orexin

    Orexin (/ ɒ ˈ r ɛ k s ɪ n /), also known as hypocretin, is a neuropeptide that regulates arousal, wakefulness, and appetite. [5] It exists in the forms of orexin-A and orexin-B.The most common form of narcolepsy, type 1, in which the individual experiences brief losses of muscle tone ("drop attacks" or cataplexy), is caused by a lack of orexin in the brain due to destruction of the cells ...

  5. Professor wins prize for discovering causes of narcolepsy ...

    www.aol.com/news/professor-wins-prize...

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  6. Autosomal dominant cerebellar ataxia, deafness, and narcolepsy

    en.wikipedia.org/wiki/Autosomal_dominant...

    This condition was first discovered in 1995 by Melberg et al. when they described 5 members of a 4-generation Swedish family where cerebellar ataxia and sensorineural deafness presented as an autosomal dominant trait, 4 of them had narcolepsy and 2 had diabetes mellitus. The oldest members had psychiatric symptoms, neurological anomalies, and ...

  7. Idiopathic hypersomnia - Wikipedia

    en.wikipedia.org/wiki/Idiopathic_hypersomnia

    Idiopathic hypersomnia (IH) is a neurological disorder which is characterized primarily by excessive sleep and excessive daytime sleepiness (EDS). [1] Idiopathic hypersomnia was first described by Bedrich Roth in 1976, and it can be divided into two forms: polysymptomatic and monosymptomatic.

  8. Axsome Expedites Development Plan for Narcolepsy Candidate

    www.aol.com/news/axsome-expedites-development...

    Axsome (AXSM) accelerates the development plan for AXS-12 to treat narcolepsy after a Breakthrough Therapy meeting with the FDA authorities. Stock dips.

  9. Microsleep - Wikipedia

    en.wikipedia.org/wiki/Microsleep

    Microsleep is extremely dangerous when it occurs in situations that demand constant alertness, such as driving a motor vehicle or working with heavy machinery. People who experience microsleeps often remain unaware of them, instead believing themselves to have been awake the whole time, or to have temporarily lost focus.