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Other rare causes of hyperthermia include thyrotoxicosis and an adrenal gland tumor, called pheochromocytoma, both of which can cause increased heat production. [2] Damage to the central nervous system from brain hemorrhage, traumatic brain injury, status epilepticus , and other kinds of injury to the hypothalamus can also cause hyperthermia.
This is important because the core temperature of mammals can be controlled to be as close as possible to the optimal temperature for enzyme activity. The overall rate of an animal's metabolism increases by a factor of about two for every 10 °C (18 °F) rise in temperature, limited by the need to avoid hyperthermia. Endothermy does not provide ...
Clinically, it is important to distinguish between fever and hyperthermia as hyperthermia may quickly lead to death and does not respond to antipyretic medications. The distinction may however be difficult to make in an emergency setting, and is often established by identifying possible causes.
Thermoregulation is the ability of an organism to keep its body temperature within certain boundaries, even when the surrounding temperature is very different. A thermoconforming organism, by contrast, simply adopts the surrounding temperature as its own body temperature, thus avoiding the need for internal thermoregulation.
The enzyme alkaline phosphatase (ALP, alkaline phenyl phosphatase) is a phosphatase with the physiological role of dephosphorylating compounds. The enzyme is found across a multitude of organisms, prokaryotes and eukaryotes alike, with the same general function, but in different structural forms suitable to the environment they function in. Alkaline phosphatase is found in the periplasmic ...
Enzymes: Granulocytes: These cells contain a large variety of enzymes that perform a number of functions. Granules can be classified as either specific or azurophilic depending upon the contents, and are able to break down a number of substances, some of which may be plasma-derived proteins that allow these enzymes to act as inflammatory ...
This group of enzymes has a low substrate specificity and catalyzes the hydrolysis of phosphate esters in a basic environment. The major function of alkaline phosphatase is transporting chemicals across cell membranes. [1] Alkaline phosphatases are present in many human tissues, including bone, intestine, kidney, liver, placenta and white blood ...
Heat stroke or heatstroke, also known as sun-stroke, is a severe heat illness that results in a body temperature greater than 40.0 °C (104.0 °F), [4] along with red skin, headache, dizziness, and confusion. [2]