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Common side effects include headache, dizziness, feeling tired, and intestinal upset. [3] Serious side effects may include angioedema, gallstones, liver problems, and muscle breakdown. [3] Use in pregnancy and breastfeeding is of unclear safety. [5] It belongs to the fibrates group of medications and works by decreasing the breakdown of lipids ...
But some research has noted rare but serious side effects of once-weekly, 2.4-milligram (mg) semaglutide injections, such as pancreatitis, acute kidney injury, gallbladder issues, and thyroid cancer.
Less-common side effects can include excess air or gas in your stomach, burping, heartburn, indigestion, fast heartbeat, low blood sugar, low energy and fatigue, or even gallstones, Dr. Comite says.
Serious side effects may include toxic epidermal necrolysis, rhabdomyolysis, gallstones, and pancreatitis. [3] Use during pregnancy and breastfeeding is not recommended. [6] [7] It works by multiple mechanisms. [3] It was patented in 1969, and came into medical use in 1975. [8] It is available as a generic medication. [6]
An article from 2013 described the effects from overdose (in a 19-year-old female) as including vomiting, seizures and fatal cardiac toxicity. [ 18 ] In 2016, the young Russian chess player Ivan Bukavshin died of a massive overdose (or poisoning) of the drug, which was initially thought to be a stroke; the dose detected in his blood was 17 mg/kg.
In October, the MHRA told health professionals to remind patients of the side effects of the drugs, such as nausea and diarrhoea and, less commonly, gallstones and pancreatitis.
In rare cases when surgery is not possible, medication can be used to dissolve the stones or lithotripsy can be used to break them down. [7] In developed countries, 10–15% of adults experience gallstones. [4] Gallbladder and biliary-related diseases occurred in about 104 million people (1.6% of people) in 2013 and resulted in 106,000 deaths.
If you experience troubling side effects, like chronic constipation or incessant vomiting If you develop a health condition like pancreatitis or gallbladder disease If the drug isn’t working