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  2. Anti-amyloid drugs - Wikipedia

    en.wikipedia.org/wiki/Anti-amyloid_drugs

    Aducanumab, sold under the brand name Aduhelm, is an anti-amyloid drug designed to treat Alzheimer's disease. It is a monoclonal antibody that targets aggregated forms (plaque) of amyloid beta (Aβ) found in the brains of people with Alzheimer's disease to reduce its buildup. [10] It was developed by Biogen and Eisai. [11] Aducanumab is given via intravenous infusion. [5] Aducanumab was ...

  3. Tafamidis - Wikipedia

    en.wikipedia.org/wiki/Tafamidis

    Tafamidis was approved by the European Medicines Agency in November 2011, to delay peripheral nerve impairment in adults with transthyretin-related hereditary amyloidosis. [9] The U.S. Food and Drug Administration rejected the application for marketing approval in 2012, on the basis that the clinical trial did not show efficacy based on a ...

  4. Eplontersen - Wikipedia

    en.wikipedia.org/wiki/Eplontersen

    Eplontersen, sold under the brand name Wainua, is a medication used for the treatment of transthyretin-mediated amyloidosis. [3] It is a transthyretin-directed antisense oligonucleotide. [3] It was developed to treat hereditary transthyretin amyloidosis by Ionis Pharmaceuticals and AstraZeneca. [4] [5] [6] [7]

  5. New test may tell who is prone to side effects from Alzheimer ...

    www.aol.com/test-may-tell-prone-side-153000197.html

    Since July 2023, three anti-amyloid medications have been FDA-approved for the treatment of Alzheimer’s disease with more in development. A potential and serious side effect of anti-amyloid ...

  6. Erenumab - Wikipedia

    en.wikipedia.org/wiki/Erenumab

    Erenumab, which was developed by Amgen and Novartis, [5] was approved in May 2018, and was the first CGRPR antagonist to be approved by the U.S. Food and Drug Administration. [6] In 2020, it was the 234th most commonly prescribed medication in the United States, with more than 1 million prescriptions.

  7. Aducanumab - Wikipedia

    en.wikipedia.org/wiki/Aducanumab

    Aducanumab, sold under the brand name Aduhelm, is an anti-amyloid drug designed to treat Alzheimer's disease. [2] [3] It is a monoclonal antibody [3] [2] that targets aggregated forms (plaque) [4] [5] of amyloid beta (Aβ) found in the brains of people with Alzheimer's disease to reduce its buildup.

  8. Donanemab - Wikipedia

    en.wikipedia.org/wiki/Donanemab

    The most common side effects include amyloid-related imaging abnormalities and headache. [2] Donanemab was approved for medical use in the United States in July 2024. [2] [5] [6] Treatment is intended for people with mild cognitive impairment or mild dementia stage of disease, which is the same population the treatment was studied in the ...

  9. Lecanemab - Wikipedia

    en.wikipedia.org/wiki/Lecanemab

    Lecanemab may cause amyloid-related imaging abnormalities (ARIA). ARIA is often asymptomatic, but serious and life-threatening events rarely may occur.ARIA most commonly presents as temporary swelling of the brain that usually resolves over time and may be accompanied by small spots of bleeding in or on the surface of the brain, though some people may have symptoms such as headache, confusion ...

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