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Cathepsin E is an enzyme (EC 3.4.23.34) that in humans is encoded by the CTSE gene. [5] [6] [7] The enzyme is also known as slow-moving proteinase, erythrocyte membrane aspartic proteinase, SMP, EMAP, non-pepsin proteinase, cathepsin D-like acid proteinase, cathepsin E-like acid proteinase, cathepsin D-type proteinase) is an enzyme.
20788 Ensembl ENSG00000198911 ENSMUSG00000022463 UniProt Q12772 Q3U1N2 RefSeq (mRNA) NM_004599 NM_033218 RefSeq (protein) NP_004590 NP_150087 Location (UCSC) Chr 22: 41.83 – 41.91 Mb Chr 15: 82.03 – 82.09 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Sterol regulatory element-binding protein 2 (SREBP-2) also known as sterol regulatory element binding transcription factor 2 ...
The catalytic sites of cathepsin D include two critical aspartic residues (amino acid 33 and 231) located on the 14 kDa and 34kDa chains. [11] The ultimate form of mature cathepsin D is composed of 337 amino acid residues, 196 amino acid residues in the heavy chain and 141 in the light chain. These two chains are linked by the hydrophobic ...
[1] [2] Cancer, Cathepsin D is a mitogen and "it attenuates the anti-tumor immune response of decaying chemokines to inhibit the function of dendritic cells". Cathepsins B and L are involved in matrix degradation and cell invasion. [3]
Cathepsin L1 is a protein that in humans is encoded by the CTSL1 gene. [ 3 ] [ 4 ] [ 5 ] The protein is a cysteine cathepsin , a lysosomal cysteine protease that plays a major role in intracellular protein catabolism .
56175 Ensembl ENSG00000182240 ENSMUSG00000040605 UniProt Q9Y5Z0 Q9JL18 RefSeq (mRNA) NM_138992 NM_012105 NM_138991 NM_019517 RefSeq (protein) NP_036237 NP_620476 NP_620477 NP_062390 Location (UCSC) Chr 21: 41.17 – 41.28 Mb Chr 16: 97.16 – 97.24 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Beta-secretase 2 (EC 3.4.23.45, also known as Memapsin-1) is an enzyme that cleaves Glu ...
1515 13039 Ensembl ENSG00000136943 ENSMUSG00000021477 UniProt O60911 P06797 RefSeq (mRNA) NM_001333 NM_001201575 NM_009984 RefSeq (protein) NP_001188504 NP_001324 NP_034114 Location (UCSC) Chr 9: 97.03 – 97.16 Mb Chr 13: 64.51 – 64.52 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Cathepsin L2 (EC 3.4.22.43, also known as cathepsin V or cathepsin U) is a protein encoded in ...
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