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Estrone, also known as estra-1,3,5(10)-trien-3-ol-17-one, is a naturally occurring estrane steroid with double bonds at the C1, C3, and C5 positions, a hydroxyl group at the C3 position, and a ketone group at the C17 position. The name estrone was derived from the chemical terms estrin (estra-1,3,5(10)-triene) and ketone.
Estrone is a naturally occurring and bioidentical estrogen, or an agonist of the estrogen receptor, the biological target of estrogens like endogenous estradiol. [5] It is a relatively weak estrogen, with much lower activity than estradiol. [5] However, estrone is converted in the body into estradiol, which provides most or all of its ...
Often, for example in tapestries, the modello is a design at a considerably reduced scale by the main artist, which is then (after approval by the patron) worked up into a full scale cartoon by the artist or others – probably his assistants; the Raphael Cartoons are much the most famous of the few surviving examples. The weavers then worked ...
An estrogen ester is an ester of an estrogen, most typically of estradiol but also of other estrogens such as estrone, estriol, and even nonsteroidal estrogens like diethylstilbestrol. [1] [2] [3] Esterification renders estradiol into a prodrug of estradiol with increased resistance to first-pass metabolism, slightly improving its oral ...
Sprezzatura ([sprettsaˈtuːra]) is an Italian word that refers to a kind of effortless grace, the art of making something difficult look easy, or maintaining a nonchalant demeanor while performing complex tasks. The term is used in the context of fashion, where classical outfits are purposefully worn in a way that seem a bit off, as if the ...
Terrone (Italian pronunciation: [terˈroːne]; plural terroni, feminine terrona) [a] is an epithet of the Italian language with which the inhabitants of Northern and Central Italy depreciatively or jokingly indicate the inhabitants of Southern Italy. Southern Italians, in turn, call Italians from the northern regions polentoni.
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Estrin is a parent structure of the estrogen steroid hormones estradiol, estrone, and estriol, which have also been known as dihydroxyestrin, ketohydroxyestrin, and trihydroxyestrin, respectively. [ 1 ] [ 2 ]