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A PTNS device received the CE mark for urinary urgency, urinary frequency and urge incontinence and fecal incontinence in 2005. Since 2005, Uroplasty has marketed the Urgent PC Neuromodulation System. In 2015, Medtronic acquired Advanced Uro-Solutions for its PTNS therapy, and began marketing the NURO PTNM System in 2016. [15]
Tolterodine, sold under the brand name Detrol among others, is a medication used to treat frequent urination, urinary incontinence, or urinary urgency. [5] Effects are seen within an hour. [6] It is taken by mouth. [6] [7] Common side effects include headache, dry mouth, constipation, and dizziness. [6]
Vibegron is indicated for the treatment of overactive bladder with symptoms of urge urinary incontinence, urgency, and urinary frequency in adults. [ 1 ] [ 5 ] [ 6 ] Safety
While medications have been shown to be helpful with treating urinary incontinence, studies have shown that the first line treatment that's most effective against urinary incontinence is behavioral therapy. [63] Injectable bulking agents may be used to enhance urethral support, however, they are of unclear benefit. [64] [65]
Darifenacin is indicated for the treatment of overactive bladder with symptoms of urge urinary incontinence, urgency, and frequency in adults. It may also be recommended with an alpha blocker to help provide symptomatic benefit for overactive bladder and obstructive symptoms such as those likely associated with benign prostatic hyperplasia. [5]
It may help with incontinence, urinary frequency, and urinary urgency. [3] Benefits appear similar to other antimuscarinics such as oxybutynin, tolterodine, and darifenacin. [4] It is also used to treat neurogenic detrusor overactivity (NDO), a form of bladder dysfunction related to neurological impairment, in children ages two years and older. [2]
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