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Then is called a pivotal quantity (or simply a pivot). Pivotal quantities are commonly used for normalization to allow data from different data sets to be compared. It is relatively easy to construct pivots for location and scale parameters: for the former we form differences so that location cancels, for the latter ratios so that scale cancels.
A pivotal trial is typically a Phase III clinical trial in the multi-year process of clinical research intended to demonstrate and confirm the safety and efficacy of a treatment – such as a drug candidate, medical device or clinical diagnostic procedure – and to estimate the incidence of common adverse effects. [1]
Efficacy vs effectiveness [ edit ] When a study assesses efficacy, it is looking at whether the drug given in the specific manner described in the study is able to influence an outcome of interest (e.g. tumor size) in the chosen population (e.g. cancer patients with no other ongoing diseases).
A ancillary statistic is a specific case of a pivotal quantity that is computed only from the data and not from the parameters. They can be used to construct prediction intervals. They are also used in connection with Basu's theorem to prove independence between statistics. [4]
Here's why Detroit Lions OT Taylor Decker was flagged on pivotal 2-point play vs. Cowboys. Gannett. Dave Birkett, Detroit Free Press. December 31, 2023 at 12:53 AM.
In a game with high stakes for each team's playoff hopes, the Packers rolled over the hobbled 49ers, putting San Francisco's postseason in further peril.
The vital question was how to secure control for the Heartland. This question may seem pointless, since in 1904 the Russian Empire had ruled most of the area from the Volga to Eastern Siberia for centuries. But throughout the nineteenth century: The West European powers had combined, usually successfully, in the Great Game to prevent Russian ...
Vital capacity (VC) is the maximum amount of air a person can expel from the lungs after a maximum inhalation. It is equal to the sum of inspiratory reserve volume, tidal volume, and expiratory reserve volume. It is approximately equal to Forced Vital Capacity (FVC). [1] [2] A person's vital capacity can be measured by a wet or regular spirometer.