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  2. Myostatin-related muscle hypertrophy - Wikipedia

    en.wikipedia.org/wiki/Myostatin-related_muscle...

    Myostatin-related muscle hypertrophy is a rare genetic condition characterized by reduced body fat and increased skeletal muscle size. [1] Affected individuals have up to twice the usual amount of muscle mass in their bodies, but increases in muscle strength are not usually congruent. [ 2 ]

  3. Statin-associated autoimmune myopathy - Wikipedia

    en.wikipedia.org/wiki/Statin-associated...

    SAAM may affect people after long-term statin use even if they had no previous muscular side effects. [4] A differentiating feature between this and more benign statin side effects is SAAM typically has a late onset. While muscle pain (myalgia) is seen in 9-20% of patients treated with statins, it typically occurs in the first month of treatment.

  4. Statin - Wikipedia

    en.wikipedia.org/wiki/Statin

    The rate at which such events occur has been widely debated, in part because the risk/benefit ratio of statins in low-risk populations is highly dependent on the rate of adverse events. [ 70 ] [ 71 ] [ 72 ] A Cochrane meta-analysis of statin clinical trials in primary prevention found no evidence of excess adverse events among those treated ...

  5. Fewer people may need statins to prevent heart disease, new ...

    www.aol.com/news/fewer-people-may-statins...

    While it’s important to treat heart disease risks before a first event, statins can cause side effects for some, including muscle pain, headaches, sleep problems and digestive problems.

  6. New Study Says Statins Don’t Cause Muscle Pain, Despite ...

    www.aol.com/lifestyle/study-says-statins-don-t...

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  7. Myostatin - Wikipedia

    en.wikipedia.org/wiki/Myostatin

    Myostatin is a myokine that is produced and released by myocytes and acts on muscle cells to inhibit muscle growth. [7] Myostatin is a secreted growth differentiation factor that is a member of the TGF beta protein family. [8] [9] Myostatin is assembled and produced in skeletal muscle before it is released into the blood stream. [10]

  8. Statins May Help Prevent Cancer in Addition to Lowering ...

    www.aol.com/statins-may-help-prevent-cancer...

    Statins are pleiotropic drugs, meaning that they affect the body in ways beyond their primary indication. It is now widely accepted that they have anti-inflammatory effects.

  9. Acquired non-inflammatory myopathy - Wikipedia

    en.wikipedia.org/wiki/Acquired_non-inflammatory...

    Common types of myopathy due to statins include myalgia, myositis, and rhabdomyolysis. Statins induce myopathy by inhibiting protein synthesis within the muscle. [6] Statin therapy tends to not show any histopathological differences, and thus a biopsy does not reveal too much about the damage. Often, the damage is found within the mitochondria.