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  2. Autosomal dominant cerebellar ataxia, deafness, and narcolepsy

    en.wikipedia.org/wiki/Autosomal_dominant...

    Usually, people with this disorder have ataxia, mild–moderate sensorineural hearing loss, narcolepsy, and cataplexy. These symptoms start happening when an affected person is about 30 years old. [6] [7] A bit later in life, people with ADCADN start showing a decline in executive function known as dementia.

  3. Nonsyndromic deafness - Wikipedia

    en.wikipedia.org/wiki/Nonsyndromic_deafness

    Many genes related to deafness are involved in the development and function of the inner ear. Gene mutations interfere with critical steps in processing sound, resulting in hearing loss. Different mutations in the same gene can cause different types of hearing loss, and some genes are associated with both syndromic and nonsyndromic deafness.

  4. Familial Danish dementia - Wikipedia

    en.wikipedia.org/wiki/Familial_Danish_dementia

    Familial Danish dementia is an extremely rare, neurodegenerative disease characterized by progressive cataracts, loss of hearing, cerebellar ataxia, paranoid psychosis, and dementia. Neuropathological hallmarks include extensive atrophy of all areas of the brain, chronic diffuse encephalopathy , and the presence of exceedingly thin and nearly ...

  5. The Common Issue for People Over 50 That’s a ... - AOL

    www.aol.com/lifestyle/common-issue-people-over...

    Related: ‘I’m a Cardiologist. Here’s How Women Can Cut Their Heart Disease Risk in Half’ ... Further, hearing loss can contribute to the development of dementia. While experts don’t ...

  6. Experimental gene therapy allows kids with inherited deafness ...

    www.aol.com/news/experimental-gene-therapy...

    Gene therapy has allowed several children born with inherited deafness to hear. On Tuesday, the Children's Hospital of Philadelphia announced similar improvements in an 11-year-old boy treated there.

  7. ‘How long can I live on my own?’ The pros and cons of new ...

    www.aol.com/news/long-live-own-pros-cons...

    Due to an even larger risk of ARIA-E, both drugs are used with greater caution, if at all, for people with two copies of the APOE-4 gene, which indicates a genetic disposition for Alzheimer’s.

  8. Hearing loss - Wikipedia

    en.wikipedia.org/wiki/Hearing_loss

    The association between age-related hearing loss and Alzheimer's disease was found to be nonsignificant, and this finding supports the hypothesis that hearing loss is associated with dementia independent of Alzheimer pathology. [32] There are several hypotheses about the underlying causal mechanism for age-related hearing loss and cognitive ...

  9. Auditory neuropathy - Wikipedia

    en.wikipedia.org/wiki/Auditory_neuropathy

    Auditory neuropathy can occur spontaneously, or in combination with diseases like Charcot-Marie-Tooth disease and Friedreich's ataxia. AN can have either congenital or acquired causes. AN can be due to genetic factors in syndromic, non-syndromic, and mitochondrial related patterns. Approximately 40% of AN cases are estimated to have a genetic ...

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