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TOL-463 is an anti-infective medication which is under development for the treatment of bacterial vaginosis (BV) and vulvovaginal candidiasis (VVC) (vaginal yeast infection). [ 3 ] [ 1 ] [ 4 ] [ 2 ] It is a boric acid -based vaginal anti-infective enhanced with ethylenediaminetetraacetic acid (EDTA) which was designed to have improved activity ...
It can also be caused by hot tubs, abrasion, tissue, tampons, or topical medications. Foreign body vaginitis (most common foreign bodies are retained tampons or condoms) may cause extremely malodorous vaginal discharges. Treatment consists of removal, for which ring forceps may be useful. Further treatment is generally not necessary.
Ibrexafungerp, sold under the brand name Brexafemme, is an antifungal medication used to treat vulvovaginal candidiasis (VVC) (vaginal yeast infection). [1] It is taken orally (by mouth). [1] It is also currently undergoing clinical trials for other indications via an intravenous (IV) formulation. An estimated 75% of women will have at least ...
Vaginal yeast infections are due to excessive growth of Candida. [1] These yeast are normally present in the vagina in small numbers. [1] Vaginal yeast infections are typically caused by the yeast species Candida albicans. Candida albicans is a common fungus often harbored in the mouth, digestive tract, or vagina without causing adverse ...
Antiestrogen medications may also contribute to the development of atrophic vaginitis. These medications include danazol, nafarelin, and medroxyprogesterone. Additional risk factors include smokers, those who have not given birth naturally (through the vagina), and increased prolactin levels while lactation. [14]
Some experts are averse to over-the-counter antidepressants because the evidence for their effectiveness is weak compared to prescription medications and active ingredients vary among brands and ...
Miconazole is in the imidazole family of medications. [2] It works by decreasing the ability of fungi to make ergosterol, an important part of their cell membrane. [2] Miconazole was patented in 1968 and approved for medical use in 1971. [5] It is on the World Health Organization's List of Essential Medicines. [6] It is available as a generic ...
LACTIN-V is a live biopharmaceutical medication containing the vaginally important Lactobacillus crispatus which is under development for the treatment of bacterial vaginosis and recurrent urinary tract infections. [68] [69] [70] It has shown initial effectiveness in considerably reducing recurrence of bacterial vaginosis following antibiotic ...
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