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The most common side effects of GLP-1 medications ... Carrying excess body weight can lead to medical conditions like high blood pressure, high cholesterol, heart disease, heart attacks, and more ...
A Cochrane review, though, found that metformin was only slightly effective for decreasing androgen levels in women with PCOS. [125] Metformin also has significant effects on the gut microbiome, such as its effect on increasing agmatine production by gut bacteria, but the relative importance of this mechanism compared to other mechanisms is ...
2. Alleviates Hunger. Metformin improves how well your cells respond to insulin. This helps regulate your blood sugar levels and manage spikes in insulin that can trigger hunger and food cravings.
In April 2024 scientists reported the first case of reversion of type 2 diabetes by use of stem cells in a 59-year old man treated in 2021 who has since remain insulin-free. [162] [163] Replication in more patients and evidence over longer periods would be needed before considering this treatment as a possible cure.
For example, a 2017 study looked at 73 women with obesity who either took 1000mg of metformin or 360mg of orlistat — another weight loss medication — for three months. Although the group ...
Metformin is a first-line medication used for treatment of type 2 diabetes. It is generally prescribed at initial diagnosis in conjunction with exercise and weight loss, as opposed to the past, where it was prescribed after diet and exercise had failed.
Stomach and bowel issues can be metformin side effects, especially when you’re first starting out. If you work from home and are close to a bathroom, you may be fine taking your meds at any time.
Dosage changes can help address that, at the risk of side effects and complications. [104] Women with type 1 diabetes show a higher than normal rate of polycystic ovarian syndrome (PCOS). [106] The reason may be that the ovaries are exposed to high insulin concentrations since women with type 1 diabetes can have frequent hyperglycemia. [107]
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