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Goeckerman therapy is a regimen for treatment of moderate to severe plaque psoriasis using a combination of crude coal tar and artificial ultraviolet radiation.It is a specialized form of light therapy.
Guselkumab is indicated to treat moderate to severe plaque psoriasis, and psoriatic arthritis in adults. [5] Guselkumab is provided as a subcutaneous injection of 100 mg given every eight weeks (except for the second dose, which is given four weeks after the first dose). [10]
These medications are generally well-tolerated, and limited long-term outcome data have demonstrated biologics to be safe for long-term use in moderate to severe plaque psoriasis. [98] [100] However, due to their immunosuppressive actions, biologics have been associated with a small increase in the risk for infection. [98]
Risankizumab was approved by the U.S. Food and Drug Administration (FDA) for treatment of moderate-to-severe plaque psoriasis in April 2019. [13] [10] [14]The FDA approved risankizumab based on evidence primarily from five clinical trials (Trial 1/NCT02684370, Trial 2/NCT02684357, Trial 3/NCT02672852, Trial 4/ NCT02694523, and Trial 5/NCT02054481) of 1606 participants with moderate to severe ...
Icotrokinra is designed to selectively block the IL-23 receptor, which plays a vital role in the pathogenic T-cell activation of plaque psoriasis. [2] [3]The phase 3 ICONIC-LEAD trial has been evaluating icotrokinra in adult and adolescent patients aged 12 years and older with moderate-to-severe cases of plaque psoriasis.
Plaque psoriasis is a skin disease that causes raised patches or plaques of skin usually on the scalp, knees, elbows, and lower back. It’s important that you have a good skin care routine to ...
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