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  2. Midodrine - Wikipedia

    en.wikipedia.org/wiki/Midodrine

    Midodrine, also known as 3,6-dimethoxy-β-hydroxy-N-aminoethanonyl-2-phenylethylamine, is a substituted phenethylamine derivative. [4] Midodrine is an odorless, white, crystalline powder, soluble in water and sparingly soluble in methanol. [19] Midodrine's experimental log P is -0.5 and its predicted log P ranges from -0.49 to -0.95.

  3. Rectal administration - Wikipedia

    en.wikipedia.org/wiki/Rectal_administration

    Many oral forms of medications can be crushed and suspended in water to be given via a rectal catheter. The rectal route of administration is useful for patients with any digestive tract motility problem, such as dysphagia , ileus , or bowel obstruction , that would interfere with the progression of the medication through the tract.

  4. Tobacco smoke enema - Wikipedia

    en.wikipedia.org/wiki/Tobacco_smoke_enema

    His name was cited in one of the earliest documented cases of resuscitation by rectally applied tobacco smoke, from 1746, when a seemingly drowned woman was treated. On the advice of a passing sailor, the woman's husband inserted the stem of the sailor's pipe into her rectum, covered the bowl with a piece of perforated paper, and "blew hard".

  5. Prochlorperazine - Wikipedia

    en.wikipedia.org/wiki/Prochlorperazine

    Prochlorperazine can also cause a life-threatening condition called neuroleptic malignant syndrome (NMS). Some symptoms of NMS include high fever, stiff muscles, neck muscle spasms, confusion, irregular pulse or blood pressure, fast heart rate (tachycardia), sweating, and abnormal heart rhythms (arrhythmias).

  6. Alcohol enema - Wikipedia

    en.wikipedia.org/wiki/Alcohol_enema

    An alcohol enema, also known colloquially as butt-chugging or boofing, is the act of introducing alcohol into the rectum and colon via the anus, i.e., as an enema.This method of alcohol consumption can be dangerous and even deadly because it leads to faster intoxication than drinking since the alcohol is absorbed directly into the bloodstream and bypasses the body's ability to reject the toxin ...

  7. Hepatorenal syndrome - Wikipedia

    en.wikipedia.org/wiki/Hepatorenal_syndrome

    [1] [2] [29] However, one study of 13 patients with hepatorenal syndrome showed significant improvement in kidney function when the two were used together (with midodrine given orally, octreotide given subcutaneously and both dosed according to blood pressure), with three patients surviving to discharge. [30]

  8. Extended-release morphine - Wikipedia

    en.wikipedia.org/wiki/Extended-release_morphine

    Extended-release (or slow-release) formulations of morphine are those whose effect last substantially longer than bare morphine, availing for, e.g., one administration per day. Conversion between extended-release and immediate-release (or "regular") morphine is easier than conversion to or from an equianalgesic dose of another opioid with ...

  9. Pharmacokinetics of estradiol - Wikipedia

    en.wikipedia.org/wiki/Pharmacokinetics_of_estradiol

    Trough estradiol levels and MADRS Tooltip Montgomery–Åsberg Depression Rating Scale scores with 1 mg sublingual micronized estradiol 3 to 8 times per day (3 to 8 mg/day total; mean 4.8 mg/day total) in women with postpartum depression. Blood was drawn specifically in the mornings before the first dose of sublingual estradiol for the day.

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