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Besides the dose ingested, factors such as the person's total body water, speed of drinking, the drink's nutritional content, and the contents of the stomach all influence the profile of blood alcohol content (BAC) over time. Breath alcohol content (BrAC) and BAC have similar profile shapes, so most forensic pharmacokinetic calculations can be ...
Alcohol inhalation is a method of administering alcohol directly into the respiratory system, with aid of a vaporizing or nebulizing device or bag. It is chiefly applied for recreational use, when it is also referred to as alcohol smoking, but it has medical applications for testing on laboratory rats, and treatment of pulmonary edema and viral pneumonia.
After binge drinking, unconsciousness can occur and extreme levels of consumption can lead to alcohol poisoning and death (a concentration in the blood stream of 0.40% will kill half of those affected [32] [medical citation needed]). Alcohol may also cause death indirectly, by asphyxiation from vomit.
Alcoholic ketoacidosis is caused by complex physiology that is the result of prolonged and heavy alcohol intake, usually in the setting of poor nutrition. Chronic alcohol use can cause depleted hepatic glycogen stores and ethanol metabolism further impairs gluconeogenesis.
Alcohol use disorder can cause a susceptibility to infection after major trauma to the lungs / respiratory system. It creates an increased risk of aspiration of gastric acid , microbes from the upper part of the throat, decreased mucus-facilitated clearance of bacterial pathogens from the upper airway and impaired pulmonary host defenses.
Ingesting a great deal of alcohol in a short amount of time causes alcohol to quickly enter the bloodstream. [9]Mixing alcohol with normal soft drinks, rather than diet drinks, delays the dizzying effects of alcohol because the sugary mixture slows the emptying of the stomach, so that drunkenness occurs less rapidly.
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On average, for equal body weight, women have a higher body fat percentage than men. Since alcohol is absorbed into body water content, and men have more water in their bodies than women, for women there will be a higher blood alcohol concentration from the same amount of alcohol consumption. [21]