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2. Benadryl for Dogs? A Vet Explains How Much You Should Give - AOL

   www.aol.com/benadryl-dogs-vet-explains-much...

   Benadryl Doses by Use. The normal dose of Benadryl varies somewhat depending on what it is being used for: Allergies. The normal dose for allergies is 1–2 mg per pound of body weight up to every ...

3. Paradoxical reaction - Wikipedia

   en.wikipedia.org/wiki/Paradoxical_reaction

   This phenomenon can also be observed in adults who use the medication as a sleep aid. The prevalence of this paradoxical reaction is unknown, but research into the phenomenon suggests that it may be as a result of the medicine's interactions with the CYP2D6 enzyme, and that a metabolite of diphenhydramine may be to blame. [27]

4. Allergies in dogs - Wikipedia

   en.wikipedia.org/wiki/Allergies_in_dogs

   Dogs are susceptible to allergies much like their human companions. Most allergies occur in dogs over 6 months old. A dog that is repeatedly exposed to a particular allergen becomes sensitized to it, and the immune system overreacts to a subsequent exposure, most commonly manifesting in the form of skin irritation. [1]

5. Anti-allergic agent - Wikipedia

   en.wikipedia.org/wiki/Anti-allergic_agent

   First-generation antihistamines can easily cross the blood-brain barrier into the central nervous system to reach the H-1 receptors within, often causing drowsiness. [7] Second-generation antihistamines selectively bind to the peripheral H-1 receptors outside the blood-brain barrier, therefore they are less likely to cause sedation.

6. Why Is My Dog Not Responding to Treatment for His Red Skin? - AOL

   www.aol.com/why-dog-not-responding-treatment...

   This is a hypersensitivity reaction that can cause the red skin you described, without a fever, but there are also usually GI signs, like diarrhea and vomiting. About two thirds of the dogs do not ...

7. Doxylamine - Wikipedia

   en.wikipedia.org/wiki/Doxylamine

   Doxylamine and other first-generation antihistamines are the most widely used sleep medications in the world. [6] Typical side effects of doxylamine (at recommended doses) include dizziness, drowsiness, grogginess, and dry mouth, among others. [7] [4] As an antihistamine, doxylamine is an inverse agonist of the histamine H 1 receptor.