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Weight loss drugs Wegovy and Ozempic can lead to significant weight loss. But when you stop taking the drugs, the weight can come back.
“When an individual stops taking Ozempic, they will no longer experience the physiologic effects of the medication which can include blood sugar regulation, reduction in appetite and weight loss ...
Even a small amount of weight loss, such as 5-10% of your total body weight, can bring your blood pressure down, stabilize your blood sugar, improve your blood cholesterol and give you more energy.”
SGLT2 inhibitors cause the loss of 60–100 grams (2.1–3.5 oz) glucose in the urine each day and are associated with a modest, sustained weight loss of 1.5–2 kilograms (3.3–4.4 lb) in people with type 2 diabetes.
Dapagliflozin, sold under the brand names Farxiga (US) and Forxiga (EU) among others, is a medication used to treat type 2 diabetes. [ 6 ] [ 7 ] [ 10 ] It is also used to treat adults with heart failure and chronic kidney disease .
While these GLP-1 drugs are not recommended for short-term use, people stop taking them for a variety of reasons, including reaching their weight loss goals, severity of side effects, and cost.
Some studies found that dapagliflozin is associated with a decrease in body weight which is statistically superior compared to placebo or other active comparators. [50] [44] It is primarily associated with caloric rather than fluid loss. [50] [44]
But significant weight loss will generally take longer. A Novo Nordisk-funded 2021 study looked at almost 2,000 adults with excess body weight or obesity without diabetes.
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